SCHEMBL7564773

SCHEMBL7564773

C=C(C)C(=O)OC(C)Oc1ccc(OC(C)OC(=O)C(=C)C)cc1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ELANE P08246 1/20 0.41
POLB P06746 2/20 0.41
KMT2A Q03164 2/20 0.40
MAPT P10636 1/20 0.39
PARP10 Q53GL7 1/20 0.39
TSHR P16473 1/20 0.38
ATM Q13315 1/20 0.38
CYP1A2 P05177 1/20 0.37
GAA P10253 1/20 0.37
CYP2C9 P11712 1/20 0.37
PKM P14618 1/20 0.37
CYP2C19 P33261 1/20 0.37
TAS1R3 Q7RTX0 1/20 0.37
TAS1R1 Q7RTX1 1/20 0.37
TAS1R2 Q8TE23 1/20 0.37
ALDH1A1 P00352 3/20 0.37
MTNR1A P48039 2/20 0.37
MTNR1B P49286 2/20 0.37
APEX1 P27695 1/20 0.36
HTT P42858 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10870371 0.93 ELANE (0.51) ELANEPOLBKMT2AMAPTPARP10
SCHEMBL7252816 0.93 LMNA (0.43) ELANEPOLBKMT2AMAPTPARP10
SCHEMBL11662636 0.92 PARP10 (0.38) ELANEPOLBKMT2AMAPTPARP10
SCHEMBL2029289 0.92 CYP1A2 (0.42) POLBKMT2AMAPTTSHRATM
SCHEMBL548113 0.92 RAB9A (0.40) ELANEPOLBKMT2AMAPTALDH1A1
SCHEMBL21370 0.91 MTNR1A (0.45) ELANEKMT2AMAPTTSHRATM
SCHEMBL59814 0.90 AR (0.39) ELANEPOLBKMT2AMAPTPARP10
SCHEMBL8674500 0.90 KMT2A (0.57) ELANEPOLBKMT2AMAPTPARP10
SCHEMBL4161347 0.90 POLB (0.45) ELANEPOLBKMT2AMAPTTSHR
SCHEMBL9807299 0.89 CYP1A2 (0.55) ELANEMAPTCYP1A2GAACYP2C9

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0940694-B1 Photochromic curable composition TOKUYAMA CORP (JP) 2002-08-14 EP disclosed
US-6194511-B1 COMPRISING POLYMERIZABLE MONOMER CONTAINING SULFUR-CONTAINING (METH)ACRYLATE POLYMERIZABLE MONOMER AND PHOTOCHROMIC COMPOUND TOKUYAMA CORPORATION (JP) 2001-02-27 US disclosed
EP-0940694-A1 Photochromic curable composition TOKUYAMA CORPORATION (JP) 1999-09-08 EP disclosed