Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7311400 | 0.93 | AGTR1 (0.71) | AGTR1AGTR2 | |
| SCHEMBL8076001 | 0.90 | AGTR1 (0.65) | AGTR1AGTR2 | |
| SCHEMBL9294548 | 0.90 | AGTR2 (0.62) | AGTR1AGTR2 | |
| SCHEMBL1076 | 0.90 | AGTR1 (0.62) | AGTR1AGTR2 | |
| SCHEMBL7298585 | 0.90 | AGTR1 (0.72) | AGTR1AGTR2 | |
| SCHEMBL9339135 | 0.90 | AGTR1 (0.81) | AGTR1AGTR2 | |
| SCHEMBL6534661 | 0.89 | AGTR1 (0.66) | AGTR1AGTR2 | |
| SCHEMBL7314316 | 0.87 | AGTR1 (0.68) | AGTR1AGTR2 | |
| SCHEMBL396 | 0.87 | AGTR1 (0.62) | AGTR1AGTR2 | |
| SCHEMBL8858855 | 0.86 | AGTR1 (0.67) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 11 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1059843-A1 | METHOD FOR DECREASING QT DISPERSION OR INHIBITING THE PROGRESSION OF QT DISPERSION WITH AN ANGIOTENSIN II RECEPTOR ANTAGONIST | Merck & Co., Inc. (US) | 2000-12-20 | — | — | EP | claimed |
| WO-1999043210-A1 | METHOD FOR DECREASING QT DISPERSION OR INHIBITING THE PROGRESSION OF QT DISPERSION WITH AN ANGIOTENSIN II RECEPTOR ANTAGONIST | MERCK & CO., INC. (US) | 1999-09-02 | — | — | WO | claimed |
| US-5302610-A | Hypotensive agents | G. D. SEARLE & CO. (US) | 1994-04-12 | — | — | US | claimed |
| EP-0533840-A1 | TREATMENT OF CHRONIC RENAL FAILURE WITH IMIDAZOLE ANGIOTENSIN-II RECEPTOR ANTAGONISTS. | DU PONT (US) | 1993-03-31 | — | — | EP | claimed |
| WO-1992002257-A2 | RENAL-SELECTIVE ANGIOTENSIN II ANTAGONISTS FOR TREATMENT OF HYPERTENSION | G.D. SEARLE & CO. (US) | 1992-02-20 | — | — | WO | claimed |
| EP-0754042-A4 | TREATMENT OF ATHEROSCLEROSIS WITH ANGIOTENSIN II RECEPTOR BLOCKING IMIDAZOLES | MERCK & CO INC (US) | 2004-06-23 | — | — | EP | disclosed |
| EP-1059843-A1 | METHOD FOR DECREASING QT DISPERSION OR INHIBITING THE PROGRESSION OF QT DISPERSION WITH AN ANGIOTENSIN II RECEPTOR ANTAGONIST | Merck & Co., Inc. (US) | 2000-12-20 | — | — | EP | disclosed |
| WO-1999043210-A1 | METHOD FOR DECREASING QT DISPERSION OR INHIBITING THE PROGRESSION OF QT DISPERSION WITH AN ANGIOTENSIN II RECEPTOR ANTAGONIST | MERCK & CO., INC. (US) | 1999-09-02 | — | — | WO | disclosed |
| US-5646171-A | HYPOTENSIVE AGENTS | SANKYO COMPANY, LIMITED (JP) | 1997-07-08 | — | — | US | disclosed |
| US-5616599-A | HYPOTENSIVE AGENTS FOR CARDIOVASCULAR DISORDER | SANKYO COMPANY, LIMITED (JP) | 1997-04-01 | — | — | US | disclosed |
| EP-0754042-A1 | TREATMENT OF ATHEROSCLEROSIS WITH ANGIOTENSIN II RECEPTOR BLOCKING IMIDAZOLES | MERCK & CO. INC. (US) | 1997-01-22 | — | — | EP | disclosed |