Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.61 |
| ▸ | POLB | P06746 | 2/20 | 0.61 |
| ▸ | HPGD | P15428 | 3/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.55 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.55 |
| ▸ | VCAM1 | P19320 | 1/20 | 0.53 |
| ▸ | LMNA | P02545 | 2/20 | 0.53 |
| ▸ | MEN1 | O00255 | 2/20 | 0.53 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.53 |
| ▸ | RAF1 | P04049 | 1/20 | 0.52 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.52 |
| ▸ | GFER | P55789 | 1/20 | 0.52 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.52 |
| ▸ | CA1 | P00915 | 1/20 | 0.51 |
| ▸ | CA2 | P00918 | 1/20 | 0.51 |
| ▸ | TPMT | P51580 | 1/20 | 0.50 |
| ▸ | USP10 | Q14694 | 1/20 | 0.49 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.46 |
| ▸ | NPC1 | O15118 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11540771 | 0.89 | POLB (0.61) | MAPTPOLBHPGDALDH1A1NPSR1 | |
| SCHEMBL8184777 | 0.87 | TPMT (0.62) | MAPTPOLBHPGDALDH1A1LMNA | |
| SCHEMBL11543280 | 0.87 | VCAM1 (0.53) | MAPTPOLBHPGDALDH1A1NPSR1 | |
| SCHEMBL6136038 | 0.87 | MAPT (0.56) | MAPTPOLBHPGDALDH1A1NPSR1 | |
| SCHEMBL6135845 | 0.83 | MAPT (0.56) | MAPTPOLBHPGDALDH1A1NPSR1 | |
| SCHEMBL5216905 | 0.83 | TPMT (0.64) | MAPTPOLBHPGDALDH1A1NPSR1 | |
| SCHEMBL11546125 | 0.80 | POLB (0.55) | MAPTPOLBHPGDALDH1A1NPSR1 | |
| SCHEMBL11517426 | 0.80 | VCAM1 (0.46) | MAPTPOLBHPGDALDH1A1NPSR1 | |
| SCHEMBL8462586 | 0.79 | TPMT (0.59) | MAPTALDH1A1VCAM1MEN1KMT2A | |
| SCHEMBL30740961 | 0.79 | TPMT (0.59) | MAPTALDH1A1VCAM1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1003498-A4 | DI-ARYL ETHERS AND THEIR DERIVATIVES AS ANTI-CANCER AGENTS | BIOSOURCE TECH INC (US) | 2004-07-14 | — | — | EP | disclosed |
| US-6433012-B1 | ADMINISTERING METHYL DIIODO-BENZOATE DERIVATIVES AS ANGIOGENESIS INHIBITORS; REDUCING TUMOR NECROSIS FACTOR; TREATING INFLAMMATORY BOWEL AND CROHN*S DISEASE | LARGE SCALE BIOLOGY CORP. | 2002-08-13 | — | — | US | disclosed |
| WO-2002020004-A1 | METHODS FOR INHIBITING INFLAMMATORY DISEASE | LARGE SCALE BIOLOGY CORPORATION (US) | 2002-03-14 | — | — | WO | disclosed |
| EP-1063985-A1 | BENZOATES DERIVATIVES FOR INHIBITING ANGIOGENESIS | Biosource Technologies, Inc. (US) | 2001-01-03 | — | — | EP | disclosed |
| US-6169104-B1 | COMPOUNDS BIND TUBULIN AND EXHIBIT ANTI-MITOTIC PROPERTIES; USING SUCH COMPOUNDS TO INHIBIT ABNORMAL CELL MITOSIS AND, IN PARTICULAR, TO INHIBIT TUMOR CELL GROWTH | LARGE SCALE BIOLOGY CORPORATION | 2001-01-02 | — | — | US | disclosed |
| US-6150407-A | Methods for inhibiting angiogenesis | LARGE SCALE BIOLOGY CORPORATION (US) | 2000-11-21 | — | — | US | disclosed |
| EP-1003498-A1 | DI-ARYL ETHERS AND THEIR DERIVATIVES AS ANTI-CANCER AGENTS | Biosource Technologies, Inc. (US) | 2000-05-31 | — | — | EP | disclosed |
| WO-1999048495-A1 | BENZOATES DERIVATIVES FOR INHIBITING ANGIOGENESIS | BIOSOURCE TECHNOLOGIES, INC. (US) | 1999-09-30 | — | — | WO | disclosed |
| WO-1998042328-A1 | DI-ARYL ETHERS AND THEIR DERIVATIVES AS ANTI-CANCER AGENTS | BIOSOURCE TECHNOLOGIES, INC. (US) | 1998-10-01 | — | — | WO | disclosed |