Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | GRM4 | Q14833 | 1/20 | 0.46 |
| ▸ | MAPT | P10636 | 3/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.43 |
| ▸ | POLB | P06746 | 1/20 | 0.43 |
| ▸ | RAB9A | P51151 | 1/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.39 |
| ▸ | GAA | P10253 | 2/20 | 0.39 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 3/20 | 0.38 |
| ▸ | CA2 | P00918 | 3/20 | 0.38 |
| ▸ | CA9 | Q16790 | 2/20 | 0.38 |
| ▸ | CA12 | O43570 | 1/20 | 0.38 |
| ▸ | CA4 | P22748 | 1/20 | 0.38 |
| ▸ | CA6 | P23280 | 1/20 | 0.38 |
| ▸ | CA5A | P35218 | 1/20 | 0.38 |
| ▸ | CA7 | P43166 | 1/20 | 0.38 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6512600 | 0.98 | GRM4 (0.45) | GRM4MAPTKDM4ENPC1POLB | |
| SCHEMBL31623387 | 0.85 | MAPT (0.47) | GRM4MAPTKDM4ENPC1POLB | |
| SCHEMBL11680691 | 0.83 | CA1 (0.48) | MAPTKDM4ENPC1POLBRAB9A | |
| SCHEMBL3244814 | 0.82 | ALDH1A1 (0.43) | MAPTKDM4ENPC1POLBRAB9A | |
| Hydrochloric Acid SCHEMBL6517594 | 0.81 | CA1 (0.47) | MAPTKDM4ENPC1POLBRAB9A | |
| SCHEMBL8859942 | 0.80 | HSD11B1 (0.56) | GRM4NPC1ALDH1A1GAACA2 | |
| SCHEMBL6810327 | 0.79 | ALDH1A1 (0.62) | MAPTKDM4EPOLBALDH1A1L3MBTL1 | |
| SCHEMBL30712531 | 0.78 | ALDH1A1 (0.47) | GRM4MAPTKDM4EALDH1A1GAA | |
| SCHEMBL27213996 | 0.78 | ALDH1A1 (0.47) | GRM4MAPTKDM4EALDH1A1GAA | |
| SCHEMBL6514511 | 0.78 | GRM4 (0.45) | GRM4MAPTKDM4EALDH1A1L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6727238-B2 | CYCLOOXYGENASE INHIBITORS | PFIZER INC. | 2004-04-27 | — | — | US | disclosed |