Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGS2 | P35354 | 9/20 | 0.72 |
| ▸ | PTGS1 | P23219 | 9/20 | 0.60 |
| ▸ | LMNA | P02545 | 5/20 | 0.60 |
| ▸ | CXCR1 | P25024 | 4/20 | 0.60 |
| ▸ | CXCR2 | P25025 | 4/20 | 0.60 |
| ▸ | SLC22A6 | Q4U2R8 | 3/20 | 0.60 |
| ▸ | MAPT | P10636 | 2/20 | 0.60 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.60 |
| ▸ | PMP22 | Q01453 | 2/20 | 0.60 |
| ▸ | CXCL8 | P10145 | 2/20 | 0.60 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.60 |
| ▸ | RECQL | P46063 | 1/20 | 0.60 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.60 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.60 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.60 |
| ▸ | HPGD | P15428 | 1/20 | 0.60 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.60 |
| ▸ | THPO | P40225 | 1/20 | 0.60 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.60 |
| ▸ | AKR1C3 | P42330 | 3/20 | 0.55 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10411845 | 0.97 | PTGS2 (0.75) | PTGS2PTGS1LMNACXCR1CXCR2 | |
| SCHEMBL3418 | 0.97 | PTGS2 (0.75) | PTGS2PTGS1LMNACXCR1CXCR2 | |
| SCHEMBL68873 | 0.97 | PTGS2 (0.75) | PTGS2PTGS1LMNACXCR1CXCR2 | |
| SCHEMBL66842 | 0.97 | PTGS2 (0.75) | PTGS2PTGS1LMNACXCR1CXCR2 | |
| Iodide SCHEMBL3868944 | 0.97 | PTGS2 (0.75) | PTGS2PTGS1LMNACXCR1CXCR2 | |
| SCHEMBL23581099 | 0.97 | PTGS2 (0.75) | PTGS2PTGS1LMNACXCR1CXCR2 | |
| Benzene SCHEMBL28145708 | 0.97 | PTGS2 (0.75) | PTGS2PTGS1LMNACXCR1CXCR2 | |
| Ammonia Solution, Strong SCHEMBL5606719 | 0.95 | PTGS2 (0.72) | PTGS2PTGS1LMNACXCR1CXCR2 | |
| SCHEMBL9569033 | 0.95 | PTGS2 (0.72) | PTGS2PTGS1LMNACXCR1CXCR2 | |
| SCHEMBL11772458 | 0.95 | PTGS2 (0.72) | PTGS2PTGS1LMNACXCR1CXCR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-110172019-B | Metal salts of malonic acid as nucleating additives for crystalline thermoplastics | 印度石油有限公司 | 2022-03-04 | — | — | CN | disclosed |
| EP-0957919-A4 | ANALGESIC COMPOSITION FOR TREATMENT OF MIGRAINE HEADACHES | MAUSKOP ALEXANDER (US) | 2004-07-28 | — | — | EP | disclosed |
| EP-1436268-A1 | BENZOXAZINE AND BENZOTHIAZINE DERIVATIVES AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM | Dr. Reddy's Laboratories Ltd. (IN) | 2004-07-14 | — | — | EP | disclosed |
| WO-2003033481-A1 | BENZOXAZINE AND BENZOTHIAZINE DERIVATIVES AND PARMACEUTICAL COMPOSITIONS CONTAINING THEM | DR. REDDY'S LABORATORIES LTD. (IN) | 2003-04-24 | — | — | WO | disclosed |
| EP-0957919-A1 | ANALGESIC COMPOSITION FOR TREATMENT OF MIGRAINE HEADACHES | Mauskop, Alexander (US) | 1999-11-24 | — | — | EP | disclosed |
| US-5914129-A | MAGNESIUM SALT, STIMULANT, EFFERVESCING AGENT AND CARRIERS | MAUSKOP ALEXANDER (US) | 1999-06-22 | — | — | US | disclosed |
| WO-1998003179-A1 | ANALGESIC COMPOSITION FOR TREATMENT OF MIGRAINE HEADACHES | MAUSKOP ALEXANDER (US) | 1998-01-29 | — | — | WO | disclosed |
| US-5538959-A | RAPID ABSORPTION, MAGNESIUM SALT | MAUSKOP ALEXANDER (US) | 1996-07-23 | — | — | US | disclosed |