Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HRH3 | Q9Y5N1 | 3/20 | 0.86 |
| ▸ | KDR | P35968 | 1/20 | 0.66 |
| ▸ | ACHE | P22303 | 4/20 | 0.62 |
| ▸ | LTA4H | P09960 | 7/20 | 0.60 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.59 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.59 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.53 |
| ▸ | NPC1 | O15118 | 1/20 | 0.53 |
| ▸ | MAPT | P10636 | 1/20 | 0.53 |
| ▸ | CASP3 | P42574 | 1/20 | 0.53 |
| ▸ | RAB9A | P51151 | 1/20 | 0.53 |
| ▸ | SENP8 | Q96LD8 | 1/20 | 0.53 |
| ▸ | SENP7 | Q9BQF6 | 1/20 | 0.53 |
| ▸ | SENP6 | Q9GZR1 | 1/20 | 0.53 |
| ▸ | DRD3 | P35462 | 2/20 | 0.53 |
| ▸ | DRD2 | P14416 | 1/20 | 0.53 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6301198 | 0.93 | HRH3 (1.00) | HRH3KDRACHELTA4HPDGFRB | |
| SCHEMBL4065305 | 0.84 | HRH3 (0.81) | HRH3KDRKDM4ENPC1MAPT | |
| SCHEMBL6637877 | 0.83 | HRH3 (0.62) | HRH3KDRACHELTA4HDRD3 | |
| SCHEMBL6636304 | 0.83 | CLK2 (0.65) | HRH3ACHELTA4HDRD3DRD2 | |
| SCHEMBL5078012 | 0.81 | KDR (0.98) | HRH3KDRLTA4HPDGFRBPDGFRA | |
| SCHEMBL5079406 | 0.80 | KDR (1.00) | HRH3KDRLTA4HPDGFRBPDGFRA | |
| SCHEMBL5078761 | 0.80 | KDR (1.00) | HRH3KDRLTA4HPDGFRBPDGFRA | |
| SCHEMBL6295038 | 0.79 | HRH3 (0.63) | HRH3KDRKDM4ENPC1MAPT | |
| SCHEMBL4058775 | 0.79 | HRH3 (0.65) | HRH3KDRPDGFRBPDGFRAKDM4E | |
| SCHEMBL19719043 | 0.79 | CTSV (0.67) | HRH3LTA4HKDM4ENPC1MAPT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1011666-A4 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 2004-03-31 | — | — | EP | disclosed |
| US-6172100-B1 | ADMINISTERING AMINATED 1-BENZYL-2-PHENYLINDOLE DERIVATIVES; BENZYLATION | ELI LILLY AND COMPANY | 2001-01-09 | — | — | US | disclosed |
| EP-1011666-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 2000-06-28 | — | — | EP | disclosed |
| WO-1998048797-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1998-11-05 | — | — | WO | disclosed |