SCHEMBL6535122

SCHEMBL6535122

CCCCCCCC/C=C\CCCCCCCCC(O)C(CO)OC(C)=O

nearest known ligand 0.52

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
PRKCA P17252 2/20 0.49
DEGS1 O15121 1/20 0.47
DGKA P23743 1/20 0.47
PRKCE Q02156 1/20 0.45
PRKCQ Q04759 1/20 0.45
PRKCD Q05655 1/20 0.45
MAPT P10636 2/20 0.45
CNR1 P21554 2/20 0.45
FAAH O00519 1/20 0.45
ALDH1A1 P00352 1/20 0.45
HPGD P15428 1/20 0.45
CNR2 P34972 1/20 0.45
FFAR1 O14842 1/20 0.45
FFAR4 Q5NUL3 1/20 0.45
TRPV1 Q8NER1 1/20 0.44
TP53 P04637 1/20 0.44
CYP1A2 P05177 1/20 0.44
CYP2D6 P10635 1/20 0.44
CYP2C9 P11712 1/20 0.44
MAPK1 P28482 1/20 0.44

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9073583 1.00 PRKCA (0.49) PRKCADEGS1DGKAPRKCEPRKCQ
SCHEMBL10698423 0.91 PTPN1 (0.49) PRKCAMAPTFFAR1TRPV1TP53
SCHEMBL3051954 0.89 PRKCA (0.49) PRKCADEGS1DGKAPRKCEPRKCQ
SCHEMBL21810717 0.82 FFAR1 (0.64) MAPTFAAHFFAR1FFAR4CYP1A2
SCHEMBL23404958 0.82 FFAR1 (0.64) MAPTFAAHFFAR1FFAR4CYP1A2
SCHEMBL438671 0.81 PRKCA (0.53) PRKCADGKAPRKCEPRKCQPRKCD
SCHEMBL1004745 0.81 PRKCA (0.53) PRKCADGKAPRKCEPRKCQPRKCD
SCHEMBL27318663 0.80 FFAR1 (0.50) PRKCAMAPTFAAHFFAR1FFAR4
SCHEMBL27319561 0.80 FFAR1 (0.50) PRKCAMAPTFAAHFFAR1FFAR4
SCHEMBL27335881 0.80 FFAR1 (0.50) PRKCAMAPTFAAHFFAR1FFAR4

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-1995010273-A1 USE OF PROTEIN KINASE C ACTIVATORS FOR THE MANUFACTURE OF A MEDICAMENT FOR KILLING HYPOXIC TUMOR CELLS THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY (US) 1995-04-20 WO claimed
EP-1073334-A4 SEROTONIN POTENTIATION BY OLEAMIDE ANALOGS SCRIPPS RESEARCH INST (US) 2004-04-14 EP disclosed
EP-1039902-A4 INHIBITORS OF GAP JUNCTION COMMUNICATION SCRIPPS RESEARCH INST (US) 2002-07-17 EP disclosed
EP-1073334-A1 SEROTONIN POTENTIATION BY OLEAMIDE ANALOGS THE SCRIPPS RESEARCH INSTITUTE (US) 2001-02-07 EP disclosed
EP-1039902-A2 INHIBITORS OF GAP JUNCTION COMMUNICATION The Scripps Research Institute (US) 2000-10-04 EP disclosed
WO-1999055159-A1 SEROTONIN POTENTIATION BY OLEAMIDE ANALOGS THE SCRIPPS RESEARCH INSTITUTE (US) 1999-11-04 WO disclosed
WO-1999026584-A2 INHIBITORS OF GAP JUNCTION COMMUNICATION THE SCRIPPS RESEARCH INSTITUTE (US) 1999-06-03 WO disclosed
WO-1997020212-A1 TREATMENT OF INFLAMMATION BY INHIBITION OF LIPID BODY FORMATION BETH ISRAEL DEACONESS MEDICAL CENTER (US) 1997-06-05 WO disclosed