Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTPN1 | P18031 | 1/20 | 0.49 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.49 |
| ▸ | SPHK1 | Q9NYA1 | 2/20 | 0.49 |
| ▸ | LMNA | P02545 | 2/20 | 0.49 |
| ▸ | MAPT | P10636 | 2/20 | 0.49 |
| ▸ | GMNN | O75496 | 1/20 | 0.49 |
| ▸ | POLB | P06746 | 1/20 | 0.49 |
| ▸ | THPO | P40225 | 1/20 | 0.49 |
| ▸ | MTOR | P42345 | 1/20 | 0.49 |
| ▸ | BLM | P54132 | 1/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.49 |
| ▸ | TP53 | P04637 | 1/20 | 0.49 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.49 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.49 |
| ▸ | CETP | P11597 | 1/20 | 0.49 |
| ▸ | HTT | P42858 | 1/20 | 0.49 |
| ▸ | UBE2N | P61088 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.46 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.46 |
| ▸ | PRKCA | P17252 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9073583 | 0.91 | PRKCA (0.49) | CYP2D6MAPTTP53CYP1A2PRKCA | |
| SCHEMBL6535122 | 0.91 | PRKCA (0.49) | CYP2D6MAPTTP53CYP1A2PRKCA | |
| SCHEMBL12611049 | 0.87 | PTPN1 (0.49) | PTPN1CYP2D6SPHK1LMNAMAPT | |
| SCHEMBL7377052 | 0.86 | TRPV1 (0.47) | PTPN1CYP2D6SPHK1LMNAMAPT | |
| SCHEMBL27849907 | 0.86 | TRPV1 (0.47) | PTPN1CYP2D6SPHK1LMNAMAPT | |
| SCHEMBL9007930 | 0.86 | TRPV1 (0.50) | PTPN1LMNAMAPTPRKCATRPV1 | |
| SCHEMBL4551082 | 0.84 | TRPV1 (0.45) | PTPN1CYP2D6SPHK1LMNAMAPT | |
| SCHEMBL18006545 | 0.83 | TDP1 (0.50) | PTPN1SPHK1MAPTCYP3A4PRKCA | |
| SCHEMBL27275433 | 0.83 | PRKCA (0.45) | LMNAMAPTPRKCATRPV1GPR84 | |
| SCHEMBL11290778 | 0.81 | PRKCA (0.44) | LMNAMAPTPRKCATRPV1GPR84 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0284395-A2 | Novel glycerol derivative and anti-hypertensive agent | NIPPON CHEMIPHAR CO., LTD. (JP) | 1988-09-28 | — | — | EP | disclosed |