Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 6/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.35 |
| ▸ | HPGD | P15428 | 2/20 | 0.35 |
| ▸ | TP53 | P04637 | 1/20 | 0.35 |
| ▸ | APP | P05067 | 1/20 | 0.35 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.35 |
| ▸ | SNCA | P37840 | 1/20 | 0.35 |
| ▸ | BLM | P54132 | 1/20 | 0.35 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.35 |
| ▸ | GAA | P10253 | 5/20 | 0.33 |
| ▸ | MEN1 | O00255 | 3/20 | 0.33 |
| ▸ | LMNA | P02545 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.33 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.33 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.33 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3663376 | 0.76 | MEN1 (0.35) | MAPTKDM4ESMN1; SMN2HPGDTP53 | |
| SCHEMBL3674406 | 0.66 | PTK2 (0.38) | MAPTKDM4ETP53GAAMEN1 | |
| SCHEMBL2686338 | 0.63 | MAPT (0.56) | MAPTKDM4ESMN1; SMN2HPGDTP53 | |
| SCHEMBL5098425 | 0.62 | — | — | |
| SCHEMBL11640685 | 0.62 | GAA (0.33) | MAPTKDM4ESMN1; SMN2HPGDHSD17B10 | |
| SCHEMBL9519211 | 0.62 | CXCL8 (0.49) | BLMGAALMNAKMT2ACYP2C9 | |
| SCHEMBL2677107 | 0.61 | MAPT (0.71) | MAPTKDM4ESMN1; SMN2HPGDTP53 | |
| SCHEMBL11546567 | 0.61 | CXCR2 (0.43) | MAPTKDM4ESMN1; SMN2HPGDALOX15 | |
| SCHEMBL11551574 | 0.60 | CXCR2 (0.40) | MAPTMEN1LMNAKMT2AALDH1A1 | |
| SCHEMBL11741917 | 0.60 | CXCL8 (0.44) | BLMGAALMNAKMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1071667-A4 | RECEPTOR LIGANDS | SMITHKLINE BEECHAM CORP (US) | 2004-10-20 | — | — | EP | disclosed |
| US-20010016569-A1 | Receptor ligands | SMITHKLINE BEECHAM CORPORATION | 2001-08-23 | — | — | US | disclosed |
| EP-1071667-A1 | RECEPTOR LIGANDS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-01-31 | — | — | EP | disclosed |
| WO-1999052877-A1 | RECEPTOR LIGANDS | SMITHKLINE BEECHAM CORPORATION (US) | 1999-10-21 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20010016569-A1 | Receptor ligands | FCER2, FCGR2A, FCGR1A | MAPT 3759/4885KDM4E 4049/4885SMN1; SMN2 4355/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.