Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 6/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.41 |
| ▸ | CA1 | P00915 | 3/20 | 0.41 |
| ▸ | CA2 | P00918 | 3/20 | 0.41 |
| ▸ | CA9 | Q16790 | 3/20 | 0.41 |
| ▸ | HPGD | P15428 | 2/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.41 |
| ▸ | PDK2 | Q15119 | 1/20 | 0.41 |
| ▸ | PDK4 | Q16654 | 1/20 | 0.41 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.41 |
| ▸ | POLB | P06746 | 3/20 | 0.40 |
| ▸ | LMNA | P02545 | 1/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | HSD17B10 | Q99714 | 4/20 | 0.39 |
| ▸ | GAA | P10253 | 3/20 | 0.39 |
| ▸ | GLA | P06280 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 2/20 | 0.39 |
| ▸ | MAPT | P10636 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL977363 | 0.86 | KDM4E (0.44) | KDM4EALDH1A1CA1CA2CA9 | |
| SCHEMBL31172701 | 0.85 | KDM4E (0.46) | KDM4EALDH1A1CA1CA2CA9 | |
| SCHEMBL17041239 | 0.84 | ALDH1A1 (0.41) | KDM4EALDH1A1HPGDLMNATSHR | |
| SCHEMBL1987207 | 0.84 | HSD17B10 (0.51) | KDM4EALDH1A1HPGDPOLBHSD17B10 | |
| SCHEMBL20146043 | 0.83 | CA1 (0.44) | KDM4EALDH1A1CA1CA2CA9 | |
| SCHEMBL17877001 | 0.81 | CA1 (0.43) | KDM4EALDH1A1CA1CA2CA9 | |
| SCHEMBL23380419 | 0.81 | ABL1 (0.44) | KDM4EALDH1A1CA1CA2CA9 | |
| SCHEMBL29825832 | 0.81 | SOS1 (0.43) | KDM4EALDH1A1CA1CA2CA9 | |
| SCHEMBL23286523 | 0.81 | SOS1 (0.43) | KDM4EALDH1A1CA1CA2CA9 | |
| SCHEMBL6852879 | 0.80 | CA1 (0.52) | KDM4EALDH1A1CA1CA2CA9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-3814331-B9 | NOVEL LXR MODULATORS WITH BICYCLIC CORE MOIETY | ORSOBIO INC (US) | 2023-08-09 | — | — | EP | disclosed |
| EP-1011666-A4 | ANTITHROMBOTIC AGENTS | LILLY CO ELI (US) | 2004-03-31 | — | — | EP | disclosed |
| EP-0997465-B1 | Azaindole derivatives and their use as antithrombotic agents | LILLY CO ELI (US) | 2004-02-04 | — | — | EP | disclosed |
| US-6359136-B1 | AZAINDOLE COMPOUND | ELI LILLY AND COMPANY | 2002-03-19 | — | — | US | disclosed |
| US-6265416-B1 | ANTICOAGULANTS | ELI LILLY AND COMPANY | 2001-07-24 | — | — | US | disclosed |
| EP-1011666-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 2000-06-28 | — | — | EP | disclosed |
| WO-1998048797-A1 | ANTITHROMBOTIC AGENTS | ELI LILLY AND COMPANY (US) | 1998-11-05 | — | — | WO | disclosed |