SCHEMBL6535296

SCHEMBL6535296

CC(C)C[C@H](NC(=O)[C@@H](N)CCCCN)C(=O)NCC(=O)O

nearest known ligand 0.46

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
EGFR P00533 1/20 0.46
DPP8 Q6V1X1 2/20 0.44
DPP9 Q86TI2 2/20 0.44
DPP7 Q9UHL4 2/20 0.44
GNAI3 P08754 1/20 0.44
GNAO1 P09471 1/20 0.44
GNAI1 P63096 1/20 0.44
GSR P00390 1/20 0.41
OPRK1 P41145 1/20 0.41
ERAP2 Q6P179 1/20 0.41
ERAP1 Q9NZ08 1/20 0.41
LNPEP Q9UIQ6 1/20 0.41
NPY4R P50391 5/20 0.41
NPY1R P25929 4/20 0.41
NPY2R P49146 3/20 0.41
NPY5R Q15761 2/20 0.41
PTGS1 P23219 1/20 0.40
GSTK1 Q9Y2Q3 1/20 0.40
NMT2 O60551 1/20 0.40
NMT1 P30419 1/20 0.40

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6535292 1.00 EGFR (0.46) EGFRDPP8DPP9DPP7GNAI3
SCHEMBL6535211 0.99 EGFR (0.47) EGFRDPP8DPP9DPP7GNAI3
SCHEMBL6534929 0.99 EGFR (0.47) EGFRDPP8DPP9DPP7GNAI3
SCHEMBL6534934 0.99 EGFR (0.47) EGFRDPP8DPP9DPP7GNAI3
SCHEMBL6535206 0.99 EGFR (0.47) EGFRDPP8DPP9DPP7GNAI3
SCHEMBL30537471 0.95 EGFR (0.43) EGFRDPP8DPP9DPP7GNAI3
SCHEMBL30537469 0.92 EGFR (0.47) EGFRDPP8DPP9DPP7OPRK1
SCHEMBL29591854 0.91 EGFR (0.52) EGFRDPP8DPP9DPP7GNAI3
SCHEMBL29714789 0.90 ERAP2 (0.48) EGFRDPP8DPP9DPP7GSR
SCHEMBL6534852 0.88 TERT (0.45) DPP8DPP9DPP7GNAI3GNAO1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-111602822-B Liver fat synthesis inhibitor 不二制油集团控股株式会社 2024-10-01 CN disclosed
CN-111602822-B Liver fat synthesis inhibitor 不二制油集团控股株式会社 2024-10-01 CN disclosed
US-20230109312-A1 NOVEL LINKERS FOR ANTIBODY-DRUG CONJUGATES AND RELATED COMPOUNDS, COMPOSITIONS, AND METHODS OF USE IGENICA BIOTHERAPEUTICS, INC. 2023-04-06 US disclosed
US-11229711-B2 Linkers for antibody-drug conjugates and related compounds, compositions, and methods of use Magenta Therapeutics, Inc. (US) 2022-01-25 US disclosed
EP-1015482-A4 ISOLATED CANDIDA ALBICANS OLIGOPEPTIDE TRANSPORTER GENE UNIV TENNESSEE RES CORP (US) 2004-09-15 EP disclosed
US-6441134-B1 OLIGOPEPTIDE MEMBRANE TRANSPORTER WHICH IS NOT A MEMBER OF THE PEPTIDE TRANSPORT (PTR) OR ATP BINDING CASSETTE (ABC) FAMILIES; USE TARGETING ANTICANDIDAL (FUNGICIDAL) DRUGS THE UNIVERSITY OF TENNESSEE RESEARCH CORPORATION 2002-08-27 US disclosed
EP-1015482-A1 ISOLATED CANDIDA ALBICANS OLIGOPEPTIDE TRANSPORTER GENE THE UNIVERSITY OF TENNESSEE RESEARCH CORPORATION (US) 2000-07-05 EP disclosed
WO-1998034950-A1 ISOLATED CANDIDA ALBICANS OLIGOPEPTIDE TRANSPORTER GENE THE UNIVERSITY OF TENNESSEE RESEARCH CORPORATION (US) 1998-08-13 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20230109312-A1 NOVEL LINKERS FOR ANTIBODY-DRUG CONJUGATES AND RELATED COMPOUNDS, COMPOSITIONS, AND METHODS OF USE SDCBP, DCLRE1A, BCR EGFR 289/4885DPP8 2642/4885DPP9 2681/4885
US-11229711-B2 Linkers for antibody-drug conjugates and related compounds, compositions, and methods of use CLSPN, SDCBP, DCLRE1A EGFR 339/4885DPP8 2683/4885DPP9 2688/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.