SCHEMBL6535303

SCHEMBL6535303

NCCN(CCC(=O)ON1C(=O)CCC1=O)CCC(=O)ON1C(=O)CCC1=O

nearest known ligand 0.32

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
PSMB8 P28062 2/20 0.32
PSMB5 P28074 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13386962 0.92 PSMB8 (0.34) PSMB8PSMB5
SCHEMBL13069250 0.83 PSMB8 (0.35) PSMB8PSMB5
SCHEMBL26825370 0.80 BLM (0.33)
SCHEMBL8829865 0.80 CYP1A2 (0.41) PSMB8PSMB5
SCHEMBL18973863 0.79 PSMB8 (0.34) PSMB8PSMB5
SCHEMBL43576 0.78 PSMB8 (0.35) PSMB8PSMB5
SCHEMBL18768942 0.78 CYP2D6 (0.38) PSMB8PSMB5
SCHEMBL10167598 0.77
SCHEMBL15773249 0.77 KMT2A (0.39) PSMB8PSMB5
SCHEMBL26198454 0.77 KMT2A (0.39) PSMB8PSMB5

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0941120-A4 BRANCHED PEPTIDE LINKERS BRISTOL MYERS SQUIBB CO (US) 2004-08-18 EP disclosed
EP-0941120-A1 BRANCHED PEPTIDE LINKERS BRISTOL-MYERS SQUIBB COMPANY (US) 1999-09-15 EP disclosed
WO-1998019705-A1 BRANCHED PEPTIDE LINKERS BRISTOL-MYERS SQUIBB COMPANY (US) 1998-05-14 WO disclosed