SCHEMBL43576

SCHEMBL43576

O=C(CCC(=O)ON1C(=O)CCC1=O)ON1C(=O)CCC1=O

nearest known ligand 0.35

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
PSMB8 P28062 2/20 0.35
PSMB5 P28074 1/20 0.35
LMNA P02545 1/20 0.34
MGLL Q99685 3/20 0.34
KMT2A Q03164 3/20 0.32
SMN1; SMN2 Q16637 1/20 0.32
ALOX12 P18054 1/20 0.32
PARL Q9H300 1/20 0.31
ADORA3 P0DMS8 1/20 0.31
ADORA2A P29274 1/20 0.31
ADORA2B P29275 1/20 0.31
TSHR P16473 1/20 0.31
MAPK1 P28482 1/20 0.30
ATM Q13315 1/20 0.30
HPGD P15428 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL31522720 0.98 PSMB8 (0.34) PSMB8PSMB5LMNAMGLLKMT2A
Ethylene Glycol SCHEMBL999673 0.94 PSMB8 (0.36) PSMB8PSMB5LMNAMGLL
SCHEMBL14644916 0.94 PSMB8 (0.33) PSMB8PSMB5LMNAMGLLTSHR
SCHEMBL2263421 0.94 MGLL (0.35) PSMB8PSMB5LMNAMGLL
SCHEMBL6812766 0.92 PSMB8 (0.33) PSMB8PSMB5LMNAMGLLPARL
SCHEMBL43575 0.92 EGLN1 (0.36) PSMB8PSMB5LMNAMGLLKMT2A
SCHEMBL22777675 0.91 SMN1; SMN2 (0.36) PSMB8PSMB5LMNAMGLLKMT2A
SCHEMBL290461 0.91 SMN1; SMN2 (0.40) PSMB8PSMB5LMNAMGLLKMT2A
SCHEMBL34383 0.91 SMN1; SMN2 (0.36) PSMB8PSMB5LMNAMGLLKMT2A
SCHEMBL2454952 0.90 TSHR (0.50) PSMB8PSMB5LMNAKMT2ASMN1; SMN2

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Appears in 6379 patents — a generic fragment claimed broadly, so it's down-weighted as IP noise. Top by claim status then date:

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-12629445-B2 Reactive hydrogel forming formulations and related methods, including methods of preparation BARD PERIPHERAL VASCULAR, INC. (US) 2026-05-19 US claimed
EP-4104853-B1 ARGININE DEIMINASE WITH REDUCED CROSS-REACTIVITY TOWARD ADI - PEG 20 ANTIBODIES FOR CANCER TREATMENT POLARIS GROUP (KY) 2026-05-06 EP claimed
EP-4683964-A2 POLY(ETHYLENE GLYCOL) BASED DENDRIMER-LIKE HYPERBRANCHED MACROMOLECULES, METHODS OF PREPARATION AND USE THEREOF Ocular Therapeutix, Inc. (US) 2026-01-28 EP claimed
EP-4665307-A1 BIODEGRADABLE MICROPARTICLES FOR SUSTAINED DRUG DELIVERY, METHODS OF PREPARATION AND USE THEREOF Ocular Therapeutix, Inc. (US) 2025-12-24 EP claimed
EP-4667566-A1 ARGININE DEIMINASE MUTANT, COVALENT DIMER AND CONJUGATE AND USE THEREOF Peg-Bio Biopharm Co., Ltd. (Chongqing) (CN) 2025-12-24 EP claimed
WO-2025226837-A1 ANTI-BACTERIAL METALLOTHIONEIN ANTIBODIES AND USES THEREOF UNIVERSITY OF CONNECTICUT (US) 2025-10-30 WO claimed
EP-4630058-A2 CHEMICAL TISSUE ABLATION WITH HYDROGEL MATRIX AND CORRESPONDING MEDICAL APPLICATIONS Pramand LLC (US) 2025-10-15 EP claimed
US-20250295792-A1 POLYETHYLENE GLYCOL-MODIFIED FORM OF KININ OR DERIVATIVE THEREOF AND PHARMACEUTICAL USE THEREOF ZONHON BIOPHARMA INSTITUTE, INC. (CN) 2025-09-25 US claimed
EP-4582090-A2 COMPOSITION COMPRISING PEGYLATED ARGININE DEIMINASE Polaris Group (TW) 2025-07-09 EP claimed
US-20250215414-A1 COMBINATION CANCER IMMUNOTHERAPIES WITH ARGININE DEPLETION AGENTS POLARIS GROUP (KY) 2025-07-03 US claimed
WO-1998039464-A2 ADENOVIRUS VECTORS CONTAINING HETEROLOGOUS TRANSCRIPTION REGULATORY ELEMENTS AND METHODS OF USING SAME CELL GENESYS, INC. (US) 1998-09-11 WO claimed
US-5711944-A Interferon polymer conjugates ENZON, INC. (US) 1998-01-27 US claimed
EP-0730470-A1 IMPROVED INTERFERON POLYMER CONJUGATES ENZON, INC. (US) 1996-09-11 EP claimed
CN-1126441-A Amplification of vitamin B12 absorption System Using polymers BIOTECH AUSTRALIA PTY LTD (AU) 1996-07-10 CN claimed
WO-1995013090-A1 IMPROVED INTERFERON POLYMER CONJUGATES ENZON, INC. (US) 1995-05-18 WO claimed
US-5264209-A Polyoxyethylene glycol modified interleukin derivative for hematopoietic disorders and thrombocytopenia KIRIN-AMGEN, INC. (US) 1993-11-23 US claimed
EP-0442724-A2 Modified hIL-6 Kirin-Amgen, Inc. (US) 1991-08-21 EP claimed
US-4608246-A Testing for a blood group immunological reaction IMMUCOR, INC. (US) 1986-08-26 US claimed
EP-0157797-A1 DETECTING AN IMMUNOLOGICAL REACTION WITH ACTIVATED RED BLOOD CELLS (ERYTHROCYTES) IMMUCOR, INC. (US) 1985-10-16 EP claimed
WO-1985001354-A1 DETECTING AN IMMUNOLOGICAL REACTION WITH ACTIVATED RED BLOOD CELLS (ERYTHROCYTES) IMMUCOR, INC. (US) 1985-03-28 WO claimed