Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.36 |
| ▸ | BLM | P54132 | 2/20 | 0.36 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.36 |
| ▸ | LMNA | P02545 | 2/20 | 0.36 |
| ▸ | THRB | P10828 | 2/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | PLG | P00747 | 1/20 | 0.36 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.36 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.36 |
| ▸ | RECQL | P46063 | 1/20 | 0.36 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.36 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.35 |
| ▸ | PAOX | Q6QHF9 | 1/20 | 0.35 |
| ▸ | PSMB8 | P28062 | 2/20 | 0.31 |
| ▸ | PSMB5 | P28074 | 1/20 | 0.31 |
| ▸ | HPGD | P15428 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26198454 | 0.98 | KMT2A (0.39) | CYP2D6NFKB1KMT2ABLMNPSR1 | |
| SCHEMBL15773249 | 0.98 | KMT2A (0.39) | CYP2D6NFKB1KMT2ABLMNPSR1 | |
| SCHEMBL724949 | 0.98 | KMT2A (0.39) | CYP2D6NFKB1KMT2ABLMNPSR1 | |
| Bromide SCHEMBL5681816 | 0.97 | KMT2A (0.38) | CYP2D6NFKB1KMT2ABLMNPSR1 | |
| SCHEMBL8829865 | 0.95 | CYP1A2 (0.41) | CYP2D6NFKB1KMT2ABLMNPSR1 | |
| SCHEMBL290461 | 0.91 | SMN1; SMN2 (0.40) | KMT2ALMNAALDH1A1SMN1; SMN2PSMB8 | |
| SCHEMBL13192974 | 0.89 | SLC6A5 (0.39) | KMT2ALMNATHRBMEN1ALDH1A1 | |
| SCHEMBL4960230 | 0.89 | SMN1; SMN2 (0.42) | KMT2AALDH1A1SMN1; SMN2PSMB8PSMB5 | |
| SCHEMBL905722 | 0.89 | SMN1; SMN2 (0.42) | KMT2AALDH1A1SMN1; SMN2PSMB8PSMB5 | |
| SCHEMBL379163 | 0.89 | SMN1; SMN2 (0.42) | KMT2AALDH1A1SMN1; SMN2PSMB8PSMB5 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 22 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118290484-A | Amphiphilic platinum-based complex and preparation method and application thereof | 中国药科大学 | 2024-07-05 | — | — | CN | disclosed |
| US-11058775-B2 | Insulin dimer-incretin conjugates | MERCK SHARP & DOHME CORP. (US) | 2021-07-13 | — | — | US | disclosed |
| US-10953076-B2 | Insulin receptor partial agonists and GLP-1 analogues | MERCK SHARP & DOHME CORP. (US) | 2021-03-23 | — | — | US | disclosed |
| EP-3166645-B1 | SITE SELECTIVE CONJUGATION OF AN OLIGONUCLEOTIDE CONJUGATE TO A METAL BINDING PROTEIN | AFFYCON APS (DK) | 2021-03-03 | — | — | EP | disclosed |
| US-10925970-B2 | Site selective conjugation of an oligonucleotide conjugate or a small molecule to a metal binding protein | AFFYCON APS (DK) | 2021-02-23 | — | — | US | disclosed |
| WO-2020225323-A1 | NEW THERAPEUTIC VECTORS AND PRODRUGS FOR TREATING CANCERS | SEEKYO (FR) | 2020-11-12 | — | — | WO | disclosed |
| US-10800827-B2 | Insulin receptor partial agonists | MERCK SHARP & DOHME CORP. (US) | 2020-10-13 | — | — | US | disclosed |
| EP-3221343-B1 | INSULIN RECEPTOR PARTIAL AGONISTS | MERCK SHARP & DOHME (US) | 2020-09-16 | — | — | EP | disclosed |
| US-10689430-B2 | Insulin receptor partial agonists | MERCK SHARP & DOHME CORP. (US) | 2020-06-23 | — | — | US | disclosed |
| EP-3666792-A2 | INSULIN RECEPTOR PARTIAL AGONISTS | MERCK SHARP & DOHME CORP. (US) | 2020-06-17 | — | — | EP | disclosed |
| US-20190192675-A1 | INSULIN DIMER-INCRETIN CONJUGATES | MERCK SHARP & DOHME CORP. (US) | 2019-06-27 | — | — | US | disclosed |
| US-20190177393-A1 | INSULIN RECEPTOR PARTIAL AGONISTS | MERCK SHARP & DOHME CORP. (US) | 2019-06-13 | — | — | US | disclosed |
| US-20190142906-A1 | INSULIN RECEPTOR PARTIAL AGONISTS AND GLP-1 ANALOGUES | MERCK SHARP & DOHME CORP. (US) | 2019-05-16 | — | — | US | disclosed |
| US-20190092833-A1 | INSULIN RECEPTOR PARTIAL AGONISTS | MERCK SHARP & DOHME CORP. (US) | 2019-03-28 | — | — | US | disclosed |
| US-10183981-B2 | Insulin receptor partial agonists | MERCK SHARP & DOHME LLC | 2019-01-22 | — | — | US | disclosed |
| US-10017556-B2 | Insulin receptor partial agonists | MERCK SHARP & DOHME CORP. (US) | 2018-07-10 | — | — | US | disclosed |
| US-20170354743-A1 | SITE SELECTIVE CONJUGATION OF AN OLIGONUCLEOTIDE CONJUGATE OR A SMALL MOLECULE TO A METAL BINDING PROTEIN | AFFYCON APS (DK) | 2017-12-14 | — | — | US | disclosed |
| US-20170355743-A1 | INSULIN RECEPTOR PARTIAL AGONISTS | MERCK SHARP & DOHME CORP. (US) | 2017-12-14 | — | — | US | disclosed |
| WO-2017205191-A1 | INSULIN RECEPTOR PARTIAL AGONISTS AND GLP-1 ANALOGUES | MERCK SHARP & DOHME CORP. (US) | 2017-11-30 | — | — | WO | disclosed |
| US-20170107268-A1 | INSULIN RECEPTOR PARTIAL AGONISTS | MERCK SHARP & DOHME CORP. (US) | 2017-04-20 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (14 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-10925970-B2 | Site selective conjugation of an oligonucleotide conjugate or a small molecule to a metal binding protein | CD2BP2, CACYBP, CALCOCO2 | CYP2D6 4760/4885NFKB1 1918/4885KMT2A 2326/4885 |
| US-10800827-B2 | Insulin receptor partial agonists | INSR, GPR119, IRS1 | CYP2D6 2972/4885NFKB1 2092/4885KMT2A 4174/4885 |
| US-20190192675-A1 | INSULIN DIMER-INCRETIN CONJUGATES | IAPP, GLP1R, GIPR | CYP2D6 3424/4885NFKB1 3046/4885KMT2A 4623/4885 |
| US-20190177393-A1 | INSULIN RECEPTOR PARTIAL AGONISTS | INSR, GPR119, IRS1 | CYP2D6 2972/4885NFKB1 2092/4885KMT2A 4174/4885 |
| US-20190092833-A1 | INSULIN RECEPTOR PARTIAL AGONISTS | INSR, GPR119, IRS1 | CYP2D6 2972/4885NFKB1 2092/4885KMT2A 4174/4885 |
| US-10689430-B2 | Insulin receptor partial agonists | INSR, GPR119, IRS1 | CYP2D6 2972/4885NFKB1 2092/4885KMT2A 4174/4885 |
| US-11058775-B2 | Insulin dimer-incretin conjugates | IAPP, GLP1R, GIPR | CYP2D6 3424/4885NFKB1 3046/4885KMT2A 4623/4885 |
| US-20190142906-A1 | INSULIN RECEPTOR PARTIAL AGONISTS AND GLP-1 ANALOGUES | GLP1R, GIPR, IAPP | CYP2D6 3560/4885NFKB1 4467/4885KMT2A 2161/4885 |
| US-10953076-B2 | Insulin receptor partial agonists and GLP-1 analogues | GLP1R, GIPR, IAPP | CYP2D6 3560/4885NFKB1 4467/4885KMT2A 2161/4885 |
| US-10183981-B2 | Insulin receptor partial agonists | INSR, GPR119, IRS1 | CYP2D6 2972/4885NFKB1 2092/4885KMT2A 4174/4885 |
| US-20170355743-A1 | INSULIN RECEPTOR PARTIAL AGONISTS | INSR, GPR119, IRS1 | CYP2D6 2972/4885NFKB1 2092/4885KMT2A 4174/4885 |
| US-10017556-B2 | Insulin receptor partial agonists | INSR, GPR119, IRS1 | CYP2D6 2972/4885NFKB1 2092/4885KMT2A 4174/4885 |
| US-20170107268-A1 | INSULIN RECEPTOR PARTIAL AGONISTS | INSR, GPR119, IRS1 | CYP2D6 2972/4885NFKB1 2092/4885KMT2A 4174/4885 |
| US-20170354743-A1 | SITE SELECTIVE CONJUGATION OF AN OLIGONUCLEOTIDE CONJUGATE OR A SMALL MOLECULE TO A METAL BINDING PROTEIN | CD2BP2, CACYBP, CALCOCO2 | CYP2D6 4760/4885NFKB1 1918/4885KMT2A 2326/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.