SCHEMBL6535312

SCHEMBL6535312

CCCCOC(F)=C(F)F

nearest known ligand 0.48

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 1/20 0.48
CA12 O43570 3/20 0.44
CA1 P00915 3/20 0.44
CA2 P00918 3/20 0.44
CA9 Q16790 3/20 0.44
ATM Q13315 1/20 0.44
TSHR P16473 4/20 0.41
HPGD P15428 1/20 0.41
HCAR2 Q8TDS4 1/20 0.39
ESR1 P03372 7/20 0.38
NAAA Q02083 1/20 0.38
TDP1 Q9NUW8 1/20 0.38
L3MBTL1 Q9Y468 1/20 0.38
ADRB2 P07550 1/20 0.38
ADRB1 P08588 1/20 0.38
ADRB3 P13945 1/20 0.38
EPHX1 P07099 1/20 0.35
LMNA P02545 1/20 0.35
CYP1A2 P05177 1/20 0.35
CYP2D6 P10635 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL68566 0.92 CA12 (0.54) ALDH1A1CA12CA1CA2CA9
Fluoride SCHEMBL27793234 0.81 HCAR2 (0.33) ALDH1A1CA12CA1CA2CA9
SCHEMBL28407240 0.81 CA12 (0.44) ALDH1A1CA12CA1CA2CA9
SCHEMBL1100981 0.78 ALDH1A1 (0.43) ALDH1A1CA12CA1CA2CA9
SCHEMBL2370192 0.78
SCHEMBL2623205 0.77 ALDH1A1 (0.38) ALDH1A1CA12CA1CA2CA9
SCHEMBL29760563 0.77 ALDH1A1 (0.41) ALDH1A1CA12CA1CA2CA9
SCHEMBL10071488 0.75 ALDH1A1 (0.41) ALDH1A1CA12CA1CA2CA9
SCHEMBL10071487 0.75 ALDH1A1 (0.41) ALDH1A1CA12CA1CA2CA9
SCHEMBL628549 0.74

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 30 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-104583763-B Sensor elements and methods of making and using the same 3M创新有限公司 2017-03-08 CN disclosed
CN-104487831-B Humidity sensor and sensor element 3M创新有限公司 2016-09-07 CN disclosed
CN-104487831-A Humidity sensor and sensor element 3M INNOVATIVE PROPERTIES CO 2015-04-01 CN disclosed
EP-1196465-A4 FLUOROPOLYMERS CONTAINING ORGANO-SILANES AND METHODS OF MAKING THE SAME ATOFINA CHEM INC (US) 2004-12-29 EP disclosed
US-6710123-B1 CHEMICAL RESISTANCE, HIGH TEMPERATURE STABILITY, HIGH TENSILE STRENGTH, AND/OR LOW REFRACTIVE INDICES ATOFINA CHEMICALS, INC. 2004-03-23 US disclosed
EP-0808335-B1 AMORPHOUS TETRAFLUOROETHYLENE-HEXAFLUOROPROPYLENE COPOLYMERS DU PONT (US) 2002-12-11 EP disclosed
US-6486280-B1 Amorphous tetrafluoroethylene-hexafluoropropylene copolymers E. I. DU PONT DE NEMOURS AND COMPANY 2002-11-26 US disclosed
EP-1196465-A1 FLUOROPOLYMERS CONTAINING ORGANO-SILANES AND METHODS OF MAKING THE SAME Atofina Chemicals, Inc. (US) 2002-04-17 EP disclosed
WO-2001034670-A1 FLUOROPOLYMERS CONTAINING ORGANO-SILANES AND METHODS OF MAKING THE SAME ATOFINA CHEMICALS, INC. (US) 2001-05-17 WO disclosed
US-6133389-A COATING, ENCAPSULANT COMPRISING FLUOROPOLYMER BLEND E. I. DU PONT DE NEMOURS AND COMPANY (US) 2000-10-17 US disclosed
WO-1996024624-A2 AMORPHOUS TETRAFLUOROETHYLENE-HEXAFLUOROPROPYLENE COPOLYMERS E.I. DU PONT DE NEMOURS AND COMPANY (US) 1996-08-15 WO disclosed
EP-0536562-B1 Fluoro-polymers containing blocked phenols, process for their preparation and curable compositions containing them BAYER AG (DE) 1996-05-08 EP disclosed
EP-0489314-B1 Non-crosslinked copolymers with reactive double bonds made of fluoro monomers and alcenyl-(iso)cyanurates BAYER AG (DE) 1996-04-10 EP disclosed
EP-0514674-B1 Non-crosslinked copolymers with reactive double bonds made of fluoro-monomers and of non-conjugated dienes and process for their preparation BAYER AG (DE) 1995-07-19 EP disclosed
US-5247036-A Crosslinking is possible forming a dimensional stable polymer for molding materials BAYER AKTIENGESELLSCHAFT (DE) 1993-09-21 US disclosed
US-5214115-A UNCROSSLINKED COPOLYMERS CONTAINING REACTIVE DOUBLE BONDS OF FLUORINE MONOMERS AND UNCONJUGATED DIENES AND A PROCESS FOR THEIR PRODUCTION BAYER AKTIENGESELLSCHAFT (DE) 1993-05-25 US disclosed
EP-0536562-A1 Fluoro-polymers containing blocked phenols, process for their preparation and curable compositions containing them BAYER AG (DE) 1993-04-14 EP disclosed
EP-0514674-A1 Non-crosslinked copolymers with reactive double bonds made of fluoro-monomers and of non-conjugated dienes and process for their preparation BAYER AG (DE) 1992-11-25 EP disclosed
EP-0489314-A1 Non-crosslinked copolymers with reactive double bonds made of fluoro monomers and alcenyl-(iso)cyanurates BAYER AG (DE) 1992-06-10 EP disclosed
US-4267098-A OPTIONALLY ALSO CONTAINING A COPOLYMERIZABLE MONOMER AND PHOSPHORUS ACID SALTS HOECHST AKTIENGESELLSCHAFT (DE) 1981-05-12 US disclosed