⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL3826889 | 0.72 | — | — | |
| SCHEMBL6247612 | 0.67 | — | — | |
| SCHEMBL6535315 | 0.65 | — | — | |
| SCHEMBL5667187 | 0.64 | — | — | |
| SCHEMBL29800 | 0.64 | — | — | |
| SCHEMBL9911578 | 0.59 | — | — | |
| SCHEMBL379482 | 0.59 | — | — | |
| SCHEMBL279294 | 0.59 | — | — | |
| SCHEMBL7642778 | 0.59 | — | — | |
| Methylglyoxal SCHEMBL47032 | 0.59 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-115916978-A | Oligonucleotides | 哈德森医学研究所 | 2023-04-04 | — | — | CN | disclosed |
| CN-114555095-A | Methods of treating muscular dystrophy using inhibitory oligonucleotides against CD49d | 反义治疗有限公司 | 2022-05-27 | — | — | CN | disclosed |
| CN-112368001-A | Therapeutic uses and methods | 反义治疗有限公司 | 2021-02-12 | — | — | CN | disclosed |
| EP-2938624-A1 | D-ALANINE ESTER OF SP-NUCLEOSIDE ANALOG | IDENIX Pharmaceuticals, Inc. (US) | 2015-11-04 | — | — | EP | disclosed |
| EP-2920195-A1 | D-ALANINE ESTER OF RP-NUCLEOSIDE ANALOG | IDENIX Pharmaceuticals, Inc. (US) | 2015-09-23 | — | — | EP | disclosed |
| WO-2014078436-A1 | D-ALANINE ESTER OF SP-NUCLEOSIDE ANALOG | IDENIX PHARMACEUTICALS, INC. (US) | 2014-05-22 | — | — | WO | disclosed |
| WO-2014078427-A1 | D-ALANINE ESTER OF RP-NUCLEOSIDE ANALOG | IDENIX PHARMACEUTICALS, INC. (US) | 2014-05-22 | — | — | WO | disclosed |
| EP-1084134-A4 | ACTIVATORS FOR OLIGONUCLEOTIDE SYNTHESIS | ISIS PHARMACEUTICALS INC (US) | 2004-05-26 | — | — | EP | disclosed |
| EP-1084134-A1 | ACTIVATORS FOR OLIGONUCLEOTIDE SYNTHESIS | ISIS PHARMACEUTICALS, INC. (US) | 2001-03-21 | — | — | EP | disclosed |
| WO-1999062922-A1 | ACTIVATORS FOR OLIGONUCLEOTIDE SYNTHESIS | ISIS PHARMACEUTICALS, INC. (US) | 1999-12-09 | — | — | WO | disclosed |