⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10497501 | 0.73 | — | — | |
| SCHEMBL8875892 | 0.67 | ALDH1A1 (0.33) | — | |
| SCHEMBL8464139 | 0.67 | ALDH1A1 (0.39) | — | |
| SCHEMBL8464142 | 0.67 | ALDH1A1 (0.39) | — | |
| SCHEMBL25631064 | 0.67 | ALDH1A1 (0.39) | — | |
| SCHEMBL25240738 | 0.65 | — | — | |
| SCHEMBL1771938 | 0.65 | — | — | |
| SCHEMBL6535329 | 0.65 | — | — | |
| SCHEMBL3081306 | 0.65 | — | — | |
| SCHEMBL11261334 | 0.63 | MEN1 (0.37) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1084134-A4 | ACTIVATORS FOR OLIGONUCLEOTIDE SYNTHESIS | ISIS PHARMACEUTICALS INC (US) | 2004-05-26 | — | — | EP | disclosed |
| EP-1084134-A1 | ACTIVATORS FOR OLIGONUCLEOTIDE SYNTHESIS | ISIS PHARMACEUTICALS, INC. (US) | 2001-03-21 | — | — | EP | disclosed |
| WO-1999062922-A1 | ACTIVATORS FOR OLIGONUCLEOTIDE SYNTHESIS | ISIS PHARMACEUTICALS, INC. (US) | 1999-12-09 | — | — | WO | disclosed |
| WO-1996040704-A1 | PYRAZOLE-RELATED DERIVATIVES ENDOWED WITH ANTITUMOR AND ANTIVIRAL ACTIVITIES, PROCEDURES FOR THEIR PREPARATION, PHARMACEUTICAL FORMULATIONS CONTAINING THEM | SARDINIAN ANTIVIRAL RESEARCH CONSORTIUM SARC S.C.R.L. (IT) | 1996-12-19 | — | — | WO | disclosed |