Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AR | P10275 | 14/20 | 0.54 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | RAB9A | P51151 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.47 |
| ▸ | POLB | P06746 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MAPT | P10636 | 2/20 | 0.44 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7351608 | 0.75 | NPC1 (0.53) | ARNPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL6535573 | 0.74 | GSTP1 (0.53) | SMN1; SMN2ALDH1A1CYP1A2 | |
| SCHEMBL6535826 | 0.74 | CHEK1 (0.46) | NPC1RAB9ASMN1; SMN2KMT2APOLB | |
| SCHEMBL12319823 | 0.73 | AR (0.57) | ARNPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL14919117 | 0.73 | NPC1 (0.46) | ARNPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL16310381 | 0.72 | AR (0.59) | ARNPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL17178921 | 0.71 | AR (0.62) | ARNPC1KMT2AMEN1MAPT | |
| SCHEMBL17178926 | 0.71 | AR (0.66) | ARNPC1KMT2AMEN1MAPT | |
| SCHEMBL25180669 | 0.71 | AR (0.48) | ARNPC1RAB9ASMN1; SMN2KMT2A | |
| SCHEMBL6535782 | 0.71 | MCL1 (0.50) | KDM4E |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1261338-A4 | COMPOSITIONS AND METHODS FOR TREATMENT OF EPILEPSY | CYMAR INC (US) | 2004-05-06 | — | — | EP | claimed |
| EP-1261338-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF EPILEPSY | Cymar, Inc. (US) | 2002-12-04 | — | — | EP | claimed |
| WO-2001062253-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF EPILEPSY | CYMAR, INC. (US) | 2001-08-30 | — | — | WO | claimed |
| EP-1261338-A4 | COMPOSITIONS AND METHODS FOR TREATMENT OF EPILEPSY | CYMAR INC (US) | 2004-05-06 | — | — | EP | disclosed |
| EP-1261338-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF EPILEPSY | Cymar, Inc. (US) | 2002-12-04 | — | — | EP | disclosed |
| WO-2001062253-A1 | COMPOSITIONS AND METHODS FOR TREATMENT OF EPILEPSY | CYMAR, INC. (US) | 2001-08-30 | — | — | WO | disclosed |