SCHEMBL6535579

SCHEMBL6535579

Cc1ccc(Nc2ccc(C)c3c2C2(OC3=O)c3ccccc3Oc3ccccc32)c(C)c1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 2/20 0.41
P2RY2 P41231 1/20 0.38
P2RY4 P51582 1/20 0.38
RAB9A P51151 3/20 0.37
MAPT P10636 3/20 0.37
ALDH1A1 P00352 2/20 0.37
NPC1 O15118 1/20 0.37
GAA P10253 1/20 0.37
HPGD P15428 2/20 0.37
CYP2C9 P11712 1/20 0.37
ALOX15 P16050 1/20 0.37
ALOX12 P18054 1/20 0.37
BRCA1 P38398 1/20 0.37
HSD17B10 Q99714 1/20 0.37
NPSR1 Q6W5P4 1/20 0.36
RAPGEF4 Q8WZA2 1/20 0.35
KMT2A Q03164 3/20 0.34
MEN1 O00255 2/20 0.34
SMN1; SMN2 Q16637 1/20 0.34
HTT P42858 3/20 0.34

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL10640419 0.93 P2RY2 (0.38) LMNAP2RY2P2RY4RAB9AMAPT
SCHEMBL6535406 0.88 NPSR1 (0.38) LMNAP2RY2P2RY4MAPTALDH1A1
SCHEMBL11023595 0.87 NPC1 (0.39) LMNAP2RY2P2RY4RAB9AMAPT
SCHEMBL5685570 0.87 LMNA (0.42) LMNAP2RY2P2RY4RAB9AMAPT
SCHEMBL10637028 0.86 LMNA (0.44) LMNAP2RY2P2RY4RAB9AMAPT
SCHEMBL3974160 0.85 ALDH1A1 (0.39) LMNARAB9AMAPTALDH1A1NPC1
SCHEMBL6439279 0.84 ALDH1A1 (0.37) LMNAMAPTALDH1A1HPGDCYP2C9
SCHEMBL10640227 0.83 ALDH1A1 (0.36) LMNAP2RY2P2RY4RAB9AMAPT
SCHEMBL10884503 0.82 LMNA (0.40) LMNARAB9AMAPTALDH1A1NPC1
SCHEMBL10633824 0.80 LMNA (0.44) LMNAP2RY2P2RY4MAPTALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1161504-A4 COLOR FORMER COMPOSITION AND MICROCAPSULES CONTAINING THE COMPOSITION ESCO COMPANY (US) 2004-12-01 EP claimed
EP-1161504-A1 COLOR FORMER COMPOSITION AND MICROCAPSULES CONTAINING THE COMPOSITION Esco Company (US) 2001-12-12 EP claimed
WO-2000049096-A1 COLOR FORMER COMPOSITION AND MICROCAPSULES CONTAINING THE COMPOSITION ESCO COMPANY (US) 2000-08-24 WO claimed