Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 3/20 | 0.43 |
| ▸ | CTSB | P07858 | 1/20 | 0.39 |
| ▸ | FOLH1 | Q04609 | 1/20 | 0.38 |
| ▸ | METAP2 | P50579 | 1/20 | 0.37 |
| ▸ | METAP1 | P53582 | 1/20 | 0.37 |
| ▸ | DPP4 | P27487 | 2/20 | 0.34 |
| ▸ | DPP8 | Q6V1X1 | 2/20 | 0.34 |
| ▸ | DPP9 | Q86TI2 | 2/20 | 0.34 |
| ▸ | CTSK | P43235 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | SLC7A5 | Q01650 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.33 |
| ▸ | FNTA | P49354 | 3/20 | 0.33 |
| ▸ | FNTB | P49356 | 3/20 | 0.33 |
| ▸ | PGGT1B | P53609 | 2/20 | 0.33 |
| ▸ | ANPEP | P15144 | 3/20 | 0.33 |
| ▸ | RNPEP | Q9H4A4 | 2/20 | 0.33 |
| ▸ | DNPEP | Q9ULA0 | 2/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6535678 | 1.00 | CTSC (0.43) | CTSCCTSBFOLH1METAP2METAP1 | |
| SCHEMBL2183760 | 0.91 | CTSC (0.39) | CTSCCTSBFOLH1METAP2METAP1 | |
| SCHEMBL9815784 | 0.84 | CTSC (0.44) | CTSCCTSBMETAP2METAP1DPP4 | |
| SCHEMBL9514734 | 0.84 | CTSC (0.44) | CTSCMETAP2METAP1DPP4DPP8 | |
| SCHEMBL10349778 | 0.84 | CTSC (0.44) | CTSCMETAP2METAP1DPP4DPP8 | |
| SCHEMBL10441973 | 0.84 | CTSC (0.44) | CTSCMETAP2METAP1DPP4DPP8 | |
| SCHEMBL2192420 | 0.83 | FNTA (0.48) | CTSCCTSBFNTAFNTBPGGT1B | |
| SCHEMBL29010817 | 0.82 | SLC7A5 (0.45) | CTSCSLC7A5ANPEPRNPEPDNPEP | |
| SCHEMBL21625553 | 0.82 | SLC7A5 (0.45) | CTSCSLC7A5ANPEPRNPEPDNPEP | |
| SCHEMBL29010766 | 0.82 | SLC7A5 (0.45) | CTSCSLC7A5ANPEPRNPEPDNPEP |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1303290-A4 | SMALL PEPTIDES AND METHODS FOR DOWNREGULATION OF IGE | HISTATEK LLC (US) | 2004-12-08 | — | — | EP | disclosed |
| EP-1303290-A1 | SMALL PEPTIDES AND METHODS FOR DOWNREGULATION OF IGE | Histatek, LLC (US) | 2003-04-23 | — | — | EP | disclosed |
| EP-1283715-A1 | MODULATON OF ALPHA-6 INTEGRIN-MEDIATED RESPONSES | Histatek, LLC (US) | 2003-02-19 | — | — | EP | disclosed |
| EP-1162990-A4 | TREATMENT WITH SMALL PEPTIDES TO EFFECT ANTIFIBROTIC ACTIVITY | HISTATEK LLC (US) | 2002-02-06 | — | — | EP | disclosed |
| EP-1162990-A1 | TREATMENT WITH SMALL PEPTIDES TO EFFECT ANTIFIBROTIC ACTIVITY | Histatek, LLC (US) | 2001-12-19 | — | — | EP | disclosed |
| WO-2001089552-A1 | MODULATON OF ALPHA-6 INTEGRIN-MEDIATED RESPONSES | HISTATEK, LLC (US) | 2001-11-29 | — | — | WO | disclosed |
| WO-2001005420-A1 | SMALL PEPTIDES AND METHODS FOR DOWNREGULATION OF IGE | HISTATEK, LLC (US) | 2001-01-25 | — | — | WO | disclosed |
| WO-2000056349-A1 | TREATMENT WITH SMALL PEPTIDES TO EFFECT ANTIFIBROTIC ACTIVITY | HISTATEK, LLC (US) | 2000-09-28 | — | — | WO | disclosed |