Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 4/20 | 0.44 |
| ▸ | DPP7 | Q9UHL4 | 9/20 | 0.40 |
| ▸ | DPP9 | Q86TI2 | 8/20 | 0.40 |
| ▸ | DPP8 | Q6V1X1 | 7/20 | 0.40 |
| ▸ | DPP4 | P27487 | 5/20 | 0.40 |
| ▸ | METAP2 | P50579 | 1/20 | 0.38 |
| ▸ | METAP1 | P53582 | 1/20 | 0.38 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | SLC15A1 | P46059 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | FNTA | P49354 | 1/20 | 0.33 |
| ▸ | FNTB | P49356 | 1/20 | 0.33 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10349778 | 1.00 | CTSC (0.44) | CTSCDPP7DPP9DPP8DPP4 | |
| SCHEMBL10441973 | 1.00 | CTSC (0.44) | CTSCDPP7DPP9DPP8DPP4 | |
| SCHEMBL9797593 | 0.93 | METAP2 (0.42) | CTSCDPP7DPP9DPP8DPP4 | |
| SCHEMBL9797599 | 0.93 | METAP2 (0.42) | CTSCDPP7DPP9DPP8DPP4 | |
| SCHEMBL9797628 | 0.87 | DPP7 (0.50) | CTSCDPP7DPP9DPP8DPP4 | |
| SCHEMBL8991404 | 0.87 | DPP7 (0.50) | CTSCDPP7DPP9DPP8DPP4 | |
| SCHEMBL10796739 | 0.85 | DPP4 (0.46) | CTSCDPP7DPP9DPP8DPP4 | |
| SCHEMBL10723179 | 0.85 | DPP4 (0.46) | CTSCDPP9DPP8DPP4METAP2 | |
| SCHEMBL11596802 | 0.85 | CTSC (0.42) | CTSCDPP7DPP9DPP8DPP4 | |
| SCHEMBL9815784 | 0.85 | CTSC (0.44) | CTSCDPP7DPP9DPP8DPP4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 8 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0238245-B1 | 3-HALOVINYLGLYCINE ANTIBACTERIAL AGENTS | MERCK & CO. INC. (US) | 1990-06-20 | — | — | EP | claimed |
| EP-0238245-A1 | 3-Halovinylglycine antibacterial agents | MERCK & CO. INC. (US) | 1987-09-23 | — | — | EP | claimed |
| EP-0353317-B1 | TRIPEPTIDES OF N3-4-METHOXYFUMARYL-L-2,3-DIAMINOPROPANOIC ACID AND THE METHOD OF THEIR OBTAINING | POLITECHNIKA GDANSKA (PL) | 1993-10-06 | — | — | EP | disclosed |
| EP-0238245-B1 | 3-HALOVINYLGLYCINE ANTIBACTERIAL AGENTS | MERCK & CO. INC. (US) | 1990-06-20 | — | — | EP | disclosed |
| EP-0353317-A1 | Tripeptides of N3-4-methoxyfumaryl-L-2,3-diaminopropanoic acid and the method of their obtaining | POLITECHNIKA GDANSKA (PL) | 1990-02-07 | — | — | EP | disclosed |
| US-4806680-A | REACTING IN N-PROTECTED VINYLGLYCINE ESTER WITH ARYLSELENENYL HALIDE, OXIDATION THE ADDUCT, HEATING IN MINERAL ACID | MERCK & CO., INC. (US) | 1989-02-21 | — | — | US | disclosed |
| US-4727062-A | INHIBITORS OF ALANINE RACEMASE | MERCK & CO., INC. (US) | 1988-02-23 | — | — | US | disclosed |
| EP-0238245-A1 | 3-Halovinylglycine antibacterial agents | MERCK & CO. INC. (US) | 1987-09-23 | — | — | EP | disclosed |