Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CTSC | P53634 | 4/20 | 0.44 |
| ▸ | METAP2 | P50579 | 1/20 | 0.38 |
| ▸ | METAP1 | P53582 | 1/20 | 0.38 |
| ▸ | ARG1 | P05089 | 1/20 | 0.35 |
| ▸ | ARG2 | P78540 | 1/20 | 0.35 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 1/20 | 0.34 |
| ▸ | FNTA | P49354 | 2/20 | 0.33 |
| ▸ | FNTB | P49356 | 2/20 | 0.33 |
| ▸ | PGGT1B | P53609 | 1/20 | 0.33 |
| ▸ | DPP4 | P27487 | 4/20 | 0.32 |
| ▸ | DPP8 | Q6V1X1 | 4/20 | 0.32 |
| ▸ | DPP9 | Q86TI2 | 4/20 | 0.32 |
| ▸ | DPP7 | Q9UHL4 | 2/20 | 0.32 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.32 |
| ▸ | CTSS | P25774 | 1/20 | 0.32 |
| ▸ | CTSK | P43235 | 1/20 | 0.32 |
| ▸ | CTSB | P07858 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5886456 | 0.91 | FNTA (0.40) | CTSCMETAP2METAP1ARG1ARG2 | |
| SCHEMBL10441973 | 0.85 | CTSC (0.44) | CTSCMETAP2METAP1LMNATSHR | |
| SCHEMBL10349778 | 0.85 | CTSC (0.44) | CTSCMETAP2METAP1LMNATSHR | |
| SCHEMBL9514734 | 0.85 | CTSC (0.44) | CTSCMETAP2METAP1LMNATSHR | |
| SCHEMBL9815788 | 0.84 | CTSC (0.43) | CTSCMETAP2METAP1ARG1ARG2 | |
| SCHEMBL6535676 | 0.84 | CTSC (0.43) | CTSCMETAP2METAP1LMNATSHR | |
| SCHEMBL6535678 | 0.84 | CTSC (0.43) | CTSCMETAP2METAP1LMNATSHR | |
| SCHEMBL11596802 | 0.82 | CTSC (0.42) | CTSCMETAP2METAP1LMNATSHR | |
| SCHEMBL10796739 | 0.82 | DPP4 (0.46) | CTSCMETAP2METAP1LMNATSHR | |
| SCHEMBL10723179 | 0.82 | DPP4 (0.46) | CTSCMETAP2METAP1LMNATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0217529-B1 | EXPRESSION VECTORS FOR USE IN E, COLI | ELI LILLY AND COMPANY (US) | 1991-11-06 | — | — | EP | disclosed |
| EP-0217529-A1 | Expression vectors for use in E, coli | ELI LILLY AND COMPANY (US) | 1987-04-08 | — | — | EP | disclosed |