SCHEMBL6535681

SCHEMBL6535681

N#CC(C(N)=O)C(=O)C1CC1

nearest known ligand 0.36

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
EPHX1 P07099 2/20 0.31
GAA P10253 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9639879 0.78 KDM4E (0.31)
SCHEMBL20456241 0.75
SCHEMBL9638607 0.74 ALDH1A1 (0.31)
SCHEMBL9638528 0.74
SCHEMBL9639801 0.72 KMT2A (0.37) GAA
SCHEMBL9638558 0.70 DPP4 (0.33)
SCHEMBL9638683 0.70 GAA (0.36) EPHX1GAA
SCHEMBL2349667 0.69
SCHEMBL9639841 0.69 CAPN1 (0.34)
SCHEMBL12268287 0.68

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1207874-A4 METHODS OF TREATING PROLIFERATIVE DISORDERS BIOMEDICINES INC (US) 2004-02-11 EP disclosed
EP-1207874-A1 METHODS OF TREATING PROLIFERATIVE DISORDERS Biomedicines, Inc. (US) 2002-05-29 EP disclosed
WO-2000071113-A1 METHODS OF TREATING PROLIFERATIVE DISORDERS BIOMEDICINES, INC. (US) 2000-11-30 WO disclosed
US-4935434-A Antiarthritic isoxazole-4-carboxamides BRISTOL-MYERS COMPANY (US) 1990-06-19 US disclosed
EP-0326108-A1 Antiarthritic isoxazole-4-carboxamides Bristol-Myers Company (US) 1989-08-02 EP disclosed