Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL9639879 | 0.78 | KDM4E (0.31) | ALDH1A1 | |
| SCHEMBL9204753 | 0.74 | CHRNB2 (0.44) | MAPT | |
| SCHEMBL6535681 | 0.74 | EPHX1 (0.31) | — | |
| SCHEMBL9638528 | 0.73 | — | — | |
| SCHEMBL9198607 | 0.70 | MAPT (0.36) | ALDH1A1MAPT | |
| SCHEMBL9638558 | 0.69 | DPP4 (0.33) | — | |
| SCHEMBL12268287 | 0.69 | — | — | |
| SCHEMBL9639841 | 0.68 | CAPN1 (0.34) | MAPT | |
| SCHEMBL9639801 | 0.68 | KMT2A (0.37) | ALDH1A1MAPT | |
| SCHEMBL9789288 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0326107-B1 | ANTIARTHRITIC BETA-CYCLOALKYL-BETA-OXOPROPIONITRILES | Bristol-Myers Squibb Company (US) | 1992-09-02 | — | — | EP | disclosed |
| US-4888357-A | ANTIINFLAMMATORY AGENTS | BRISTOL-MYERS COMPANY (US) | 1989-12-19 | — | — | US | disclosed |
| EP-0326107-A1 | Antiarthritic beta-cycloalkyl-beta-oxopropionitriles | Bristol-Myers Squibb Company (US) | 1989-08-02 | — | — | EP | disclosed |