SCHEMBL6535707

SCHEMBL6535707

CC(=C(C(C)C)C(C)C)c1ccccc1

nearest known ligand 0.45

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ESR1 P03372 1/20 0.45
CES2 O00748 2/20 0.41
CES1 P23141 2/20 0.41
SMN1; SMN2 Q16637 3/20 0.39
NPSR1 Q6W5P4 2/20 0.39
LMNA P02545 1/20 0.39
MAPT P10636 1/20 0.39
XBP1 P17861 1/20 0.39
ATM Q13315 1/20 0.39
PTGS2 P35354 2/20 0.38
ELANE P08246 2/20 0.38
ALDH1A1 P00352 2/20 0.37
HPGD P15428 1/20 0.37
HTT P42858 1/20 0.37
RAB9A P51151 1/20 0.37
TSHR P16473 2/20 0.36
DAO P14920 1/20 0.36
NAPRT Q6XQN6 1/20 0.36
HTR2A P28223 2/20 0.35
CHRM2 P08172 1/20 0.35

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19624236 0.80 ESR1 (0.45) ESR1CES2CES1SMN1; SMN2NPSR1
SCHEMBL13651331 0.80 ESR1 (0.45) ESR1CES2CES1SMN1; SMN2NPSR1
SCHEMBL11844374 0.78 ESR1 (0.56) ESR1CES2CES1LMNAMAPT
SCHEMBL3902058 0.78 ESR1 (0.56) ESR1CES2CES1LMNAMAPT
SCHEMBL1035354 0.78 ESR1 (0.56) ESR1CES2CES1LMNAMAPT
SCHEMBL23278527 0.75 ESR1 (0.61) ESR1CES2CES1SMN1; SMN2MAPT
SCHEMBL8017607 0.74 CES2 (0.44) ESR1CES2CES1SMN1; SMN2NPSR1
SCHEMBL15171343 0.73 ESR1 (0.43) ESR1CES2CES1SMN1; SMN2NPSR1
SCHEMBL16160124 0.73 ESR1 (0.44) ESR1SMN1; SMN2NPSR1LMNAPTGS2
SCHEMBL58000 0.73 ESR1 (0.52) ESR1CES2CES1LMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0250090-B1 STORAGE STABLE LATENTLY CURABLE ACRYLIC FORMULATIONS EMPLOYING POLYMERIC HYDROPEROXIDES LOCTITE CORPORATION (US) 1992-01-29 EP claimed
EP-1219582-A4 METHOD OF DEHYDROGENATING TRIISOPROPYLBENZENE AND DIISOPROPYLBENZENE MITSUI CHEMICALS INC (JP) 2004-09-08 EP disclosed
WO-2001016062-A1 METHOD OF DEHYDROGENATING TRIISOPROPYLBENZENE AND DIISOPROPYLBENZENE MITSUI CHEMICALS, INCORPORATED (JP) 2001-03-08 WO disclosed