Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | APP | P05067 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 3/20 | 0.40 |
| ▸ | CYP1A2 | P05177 | 3/20 | 0.40 |
| ▸ | CYP3A4 | P08684 | 3/20 | 0.40 |
| ▸ | CYP2C9 | P11712 | 3/20 | 0.40 |
| ▸ | CYP2C19 | P33261 | 3/20 | 0.40 |
| ▸ | NPC1 | O15118 | 2/20 | 0.40 |
| ▸ | MEN1 | O00255 | 2/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.40 |
| ▸ | HPGD | P15428 | 2/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | CA12 | O43570 | 2/20 | 0.35 |
| ▸ | CA2 | P00918 | 2/20 | 0.35 |
| ▸ | CA9 | Q16790 | 2/20 | 0.35 |
| ▸ | RAB9A | P51151 | 1/20 | 0.35 |
| ▸ | GRM5 | P41594 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL2188992 | 0.87 | ALDH1A1 (0.48) | APPMAPTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL2188447 | 0.78 | — | — | |
| SCHEMBL2747094 | 0.74 | APP (0.57) | APPMAPTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL16953010 | 0.73 | TSHR (0.31) | ALDH1A1KDM4E | |
| SCHEMBL5183978 | 0.70 | APP (0.38) | APPMAPTCYP1A2GRM5FFAR1 | |
| SCHEMBL2747316 | 0.69 | MAPT (0.50) | APPMAPTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL5184854 | 0.69 | CYP1A2 (0.46) | APPMAPTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL2190184 | 0.69 | APP (0.44) | APPMAPTCYP1A2CYP3A4CYP2C9 | |
| Diphenylacetylene SCHEMBL20893441 | 0.69 | APP (0.71) | APPMAPTCYP1A2CYP3A4CYP2C9 | |
| SCHEMBL21858110 | 0.68 | CHAT (0.45) | APPMAPTCYP1A2CYP3A4CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1309639-A4 | COMPOSITIONS AND METHODS FOR THERMOSETTING MOLECULES IN ORGANIC COMPOSITIONS | HONEYWELL INT INC (US) | 2004-12-08 | — | — | EP | disclosed |
| WO-2004000909-A1 | COMPOSITIONS AND METHODS FOR THERMOSETTING MOLECULES IN ORGANIC COMPOSITIONS | HONEYWELL INTERNATIONAL INC. (US) | 2003-12-31 | — | — | WO | disclosed |
| EP-1309639-A1 | COMPOSITIONS AND METHODS FOR THERMOSETTING MOLECULES IN ORGANIC COMPOSITIONS | Honeywell International, Inc. (US) | 2003-05-14 | — | — | EP | disclosed |
| WO-2002008308-A1 | COMPOSITIONS AND METHODS FOR THERMOSETTING MOLECULES IN ORGANIC COMPOSITIONS | HONEYWELL INTERNATIONAL INC. (US) | 2002-01-31 | — | — | WO | disclosed |