SCHEMBL6535845

SCHEMBL6535845

N[C@@H](CC(=O)OC1CCCCC1)C(=O)OC1CCCCC1

nearest known ligand 0.50

Predicted protein targets (top 17)

geneUniProtsupporting neighboursconfidence
CYP2C19 P33261 1/20 0.50
NAAA Q02083 2/20 0.45
HTT P42858 1/20 0.44
L3MBTL1 Q9Y468 1/20 0.43
CYP19A1 P11511 3/20 0.41
EPHX1 P07099 2/20 0.41
CACNA1B Q00975 4/20 0.36
GRIK1 P39086 2/20 0.36
CA12 O43570 1/20 0.34
CA1 P00915 1/20 0.34
CA2 P00918 1/20 0.34
CA9 Q16790 1/20 0.34
MMP1 P03956 1/20 0.34
MMP9 P14780 1/20 0.34
MMP12 P39900 1/20 0.34
TYR P14679 1/20 0.34
GRIK2 Q13002 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
Hydrochloric Acid SCHEMBL30921689 0.96 CYP2C19 (0.46) CYP2C19NAAAHTTL3MBTL1CYP19A1
Hydrochloric Acid SCHEMBL30939844 0.93 CYP2C19 (0.42) CYP2C19NAAAHTTL3MBTL1CYP19A1
SCHEMBL10934269 0.90 TYR (0.39) CYP2C19NAAAHTTL3MBTL1CYP19A1
SCHEMBL2200901 0.87 GRIK1 (0.49) CYP2C19NAAAHTTL3MBTL1CYP19A1
SCHEMBL25197311 0.87 GRIK1 (0.49) CYP2C19NAAAHTTL3MBTL1CYP19A1
SCHEMBL9508342 0.86 CACNA1B (0.46) CYP2C19NAAAHTTL3MBTL1CYP19A1
SCHEMBL7780245 0.85 L3MBTL1 (0.54) CYP2C19NAAAHTTL3MBTL1CYP19A1
SCHEMBL7779238 0.85 L3MBTL1 (0.43) CYP2C19NAAAHTTL3MBTL1CYP19A1
SCHEMBL7779241 0.85 L3MBTL1 (0.43) CYP2C19NAAAHTTL3MBTL1CYP19A1
SCHEMBL7780247 0.85 L3MBTL1 (0.54) CYP2C19NAAAHTTL3MBTL1CYP19A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-118165034-A Nucleotide compound, composition and application thereof 深圳市塔吉瑞生物医药有限公司 2024-06-11 CN disclosed
EP-1233774-A4 UROTENSIN-II ANALOGS SMITHKLINE BEECHAM CORP (US) 2004-06-16 EP disclosed
EP-1233774-A1 UROTENSIN-II ANALOGS SmithKline Beecham Corporation (US) 2002-08-28 EP disclosed
WO-2001037780-A2 UROTENSIN-II ANALOGS SMITHKLINE BEECHAM CORPORATION (US) 2001-05-31 WO disclosed