SCHEMBL2200901

SCHEMBL2200901

N[C@@H](CC(=O)OC1CCCCC1)C(=O)O

nearest known ligand 0.49

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
GRIK1 P39086 6/20 0.49
CYP2C19 P33261 1/20 0.49
GRIK2 Q13002 2/20 0.46
NAAA Q02083 2/20 0.44
HTT P42858 1/20 0.42
CYP19A1 P11511 2/20 0.41
EPHX1 P07099 2/20 0.40
DPP7 Q9UHL4 1/20 0.40
L3MBTL1 Q9Y468 1/20 0.39
SLC1A3 P43003 3/20 0.39
SLC1A2 P43004 3/20 0.39
SLC1A1 P43005 3/20 0.39
GRIA1 P42261 1/20 0.39
GRIA2 P42262 1/20 0.39
GRIA4 P48058 1/20 0.39
GRIK3 Q13003 1/20 0.39
GRIK5 Q16478 1/20 0.39
GRM1 Q13255 1/20 0.37
GRM2 Q14416 1/20 0.37
GRIN2D O15399 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL25197311 1.00 GRIK1 (0.49) GRIK1CYP2C19GRIK2NAAAHTT
SCHEMBL9501504 0.98 GRIK1 (0.47) GRIK1CYP2C19GRIK2NAAAHTT
SCHEMBL3450598 0.91 GRIK1 (0.42) GRIK1CYP2C19GRIK2SLC1A3SLC1A2
SCHEMBL23883371 0.88 GRIK1 (0.42) GRIK1CYP2C19GRIK2NAAAHTT
SCHEMBL6535845 0.87 CYP2C19 (0.50) GRIK1CYP2C19GRIK2NAAAHTT
Hydrochloric Acid SCHEMBL30921689 0.84 CYP2C19 (0.46) GRIK1CYP2C19GRIK2NAAAHTT
SCHEMBL18071166 0.83 NAAA (0.49) GRIK1CYP2C19GRIK2NAAAHTT
SCHEMBL1845737 0.83 NAAA (0.49) GRIK1CYP2C19GRIK2NAAAHTT
SCHEMBL9503510 0.81 NAAA (0.47) GRIK1CYP2C19GRIK2NAAAHTT
SCHEMBL9070463 0.80 CYP2C19 (0.44) GRIK1CYP2C19GRIK2NAAAHTT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 28 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20200247858-A1 AGENTS MODULATING BETA-CATENIN FUNCTIONS AND METHODS THEREOF FOG PHARMACEUTICALS, INC. (US) 2020-08-06 US claimed
EP-3678683-A2 AGENTS MODULATING BETA-CATENIN FUNCTIONS AND METHODS THEREOF Fog Pharmaceuticals, Inc. (US) 2020-07-15 EP claimed
WO-2019051327-A2 AGENTS MODULATING BETA-CATENIN FUNCTIONS AND METHODS THEREOF FOG PHARMACEUTICALS, INC. (US) 2019-03-14 WO claimed
EP-4425181-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTE Bertis Inc (KR) 2024-09-04 EP disclosed
US-11883472-B2 Rusalatide acetate compositions AFFIRMED PHARMA, LLC (US) 2024-01-30 US disclosed
US-20240011979-A1 COMPOSITION FOR DETECTING OR MEASURING ANALYTES BERTIS INC. (KR) 2024-01-11 US disclosed
US-11834482-B2 Agents modulating beta-catenin functions and methods thereof FOG PHARMACEUTICALS, INC. (US) 2023-12-05 US disclosed
CN-113788877-B Novel insect kinin analogues and application thereof in aphid control 中国农业大学 2023-11-21 CN disclosed
CN-116829949-A Compositions for detecting or measuring analytes 伯蒂斯有限公司 2023-09-29 CN disclosed
CN-114478324-B Active compound and application thereof in side chain carboxyl compound protection 上海嘉莱多生物技术有限责任公司 2023-07-07 CN disclosed
WO-2023083291-A1 DERIVATIVE OF ASPARTIC ACID AND USE THEREOF IN TREATMENT OF METABOLIC DISEASES SUCH AS HEPATIC FIBROSIS AND NON-ALCOHOLIC HEPATITIS 深圳利沃生物医药科技有限公司 2023-05-19 WO disclosed
EP-3678683-A2 AGENTS MODULATING BETA-CATENIN FUNCTIONS AND METHODS THEREOF Fog Pharmaceuticals, Inc. (US) 2020-07-15 EP disclosed
US-10550153-B2 Peptide or pharmaceutically acceptable salt thereof, or prodrug thereof TOKYO UNIVERSITY OF PHARMACY & LIFE SCIENCES (JP) 2020-02-04 US disclosed
WO-2019051327-A2 AGENTS MODULATING BETA-CATENIN FUNCTIONS AND METHODS THEREOF FOG PHARMACEUTICALS, INC. (US) 2019-03-14 WO disclosed
EP-2345733-A1 PROCESS FOR PRODUCING N-PROTECTED AMINO ACID Kaneka Corporation (JP) 2011-07-20 EP disclosed
EP-1135398-A1 CYANOPHOSPHONAMIDES AND METHOD FOR PREPARATION Monsanto Technology LLC (US) 2001-09-26 EP disclosed
US-6218563-B1 Cyanophosphonamides and method for preparation MONSANTO COMPANY 2001-04-17 US disclosed
WO-2000032611-A1 CYANOPHOSPHONAMIDES AND METHOD FOR PREPARATION MONSANTO TECHNOLOGY LLC (US) 2000-06-08 WO disclosed
EP-0556405-A1 PSEUDOPENTAPEPTIDES WITH IMMUNOMODULATING ACTIVITY Japan Tobacco Inc. (JP) 1993-08-25 EP disclosed
WO-1993004080-A1 PSEUDOPENTAPEPTIDES WITH IMMUNOMODULATING ACTIVITY JAPAN TOBACCO INC. (JP) 1993-03-04 WO disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20200247858-A1 AGENTS MODULATING BETA-CATENIN FUNCTIONS AND METHODS THEREOF CTNNB1, CTNNBL1, CTNNA1 GRIK1 4143/4885CYP2C19 4879/4885GRIK2 4413/4885
US-10550153-B2 Peptide or pharmaceutically acceptable salt thereof, or prodrug thereof NMUR2, NMUR1, NTSR2 GRIK1 988/4885CYP2C19 2084/4885GRIK2 493/4885
US-11834482-B2 Agents modulating beta-catenin functions and methods thereof CTNNB1, CTNNBL1, CTNNA1 GRIK1 4143/4885CYP2C19 4879/4885GRIK2 4413/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.