SCHEMBL6535899

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL29831982	0.86	ALDH1A1 (0.50)	KDM4EALDH1A1HPGDGAASTAT3
	SCHEMBL68891	0.83	KDM4E (0.51)	KDM4EALDH1A1HPGDALOX15HTT
	SCHEMBL8905796	0.83	TDP1 (0.47)	KDM4EALDH1A1HPGDGAASTAT3
	SCHEMBL3841616	0.83	ALDH1A1 (0.47)	KDM4EALDH1A1HPGDGAASTAT3
	SCHEMBL8630313	0.83	KDM4E (0.51)	KDM4EALDH1A1HPGDGAASTAT3
	SCHEMBL30288437	0.83	KDM4E (0.51)	KDM4EALDH1A1HPGDGAASTAT3
	SCHEMBL2422281	0.83	ALDH1A1 (0.47)	KDM4EALDH1A1HPGDGAASTAT3
	SCHEMBL8627406	0.82	TLR8 (0.54)	KDM4EALDH1A1HPGDALOX15HTT
	SCHEMBL30693766	0.82	KDM4E (0.50)	KDM4EALDH1A1HPGDALOX15HTT
	SCHEMBL3364626	0.82	TLR8 (0.46)	KDM4EALDH1A1HPGDGAAALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.