Predicted protein targets (top 18)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.43 |
| ▸ | SCN9A | Q15858 | 12/20 | 0.42 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.40 |
| ▸ | MAPT | P10636 | 1/20 | 0.40 |
| ▸ | DRD1 | P21728 | 2/20 | 0.39 |
| ▸ | DRD2 | P14416 | 1/20 | 0.39 |
| ▸ | DRD4 | P21917 | 1/20 | 0.39 |
| ▸ | DRD5 | P21918 | 1/20 | 0.39 |
| ▸ | DRD3 | P35462 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.38 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.38 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.38 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.38 |
| ▸ | MEN1 | O00255 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL30749700 | 0.84 | MEN1 (0.37) | KDM4EDRD1DRD2DRD4DRD5 | |
| SCHEMBL29209371 | 0.84 | MEN1 (0.37) | KDM4EDRD1DRD2DRD4DRD5 | |
| SCHEMBL27908143 | 0.79 | FFAR4 (0.40) | FFAR4SCN9AL3MBTL1KDM4EMAPT | |
| SCHEMBL29788132 | 0.79 | FFAR4 (0.55) | FFAR4SCN9AL3MBTL1KDM4EMAPT | |
| SCHEMBL306822 | 0.79 | FFAR4 (0.55) | FFAR4SCN9AL3MBTL1KDM4EMAPT | |
| SCHEMBL9754385 | 0.78 | ERN1 (0.45) | L3MBTL1KDM4EMAPTALDH1A1MEN1 | |
| SCHEMBL27660143 | 0.78 | KDM4E (0.46) | FFAR4SCN9AL3MBTL1KDM4EMAPT | |
| SCHEMBL954787 | 0.76 | MEN1 (0.53) | ALDH1A1MEN1RAB9AKMT2A | |
| SCHEMBL25219191 | 0.76 | SCN9A (0.46) | FFAR4SCN9AL3MBTL1KDM4EMAPT | |
| SCHEMBL31023976 | 0.76 | ERN1 (0.36) | SCN9AKDM4EALDH1A1MEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1425015-A4 | TETRAHYDROQUINOLINE DERIVATIVES AS ANTITHROMBOTIC AGENTS | BRISTOL MYERS SQUIBB CO (US) | 2004-12-15 | — | — | EP | disclosed |
| EP-1425015-A2 | TETRAHYDROQUINOLINE DERIVATIVES AS ANTITHROMBOTIC AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-06-09 | — | — | EP | disclosed |
| WO-2003015715-A2 | TETRAHYDROQUINOLINE DERIVATIVES AS ANTITHROMBOTIC AGENTS | BRISTOL-MYERS SQUIBB COMPANY (US) | 2003-02-27 | — | — | WO | disclosed |