SCHEMBL954787

SCHEMBL954787

O=Cc1c(-c2ccccc2)cccc1-c1ccccc1

nearest known ligand 0.53

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
MEN1 O00255 2/20 0.53
KMT2A Q03164 2/20 0.53
RAB9A P51151 1/20 0.53
PTGS2 P35354 1/20 0.43
ALDH1A1 P00352 9/20 0.42
HSD17B10 Q99714 2/20 0.42
CYP2A6 P11509 2/20 0.42
TDP1 Q9NUW8 2/20 0.42
HPGD P15428 1/20 0.42
BCL2L1 Q07817 1/20 0.42
MAPK1 P28482 1/20 0.42
HNF4A P41235 1/20 0.42
HDAC4 P56524 1/20 0.41
HDAC2 Q92769 1/20 0.41
HDAC8 Q9BY41 1/20 0.41
HDAC6 Q9UBN7 1/20 0.41
BCAT2 O15382 1/20 0.40
LMNA P02545 1/20 0.40
PLK4 O00444 1/20 0.39
MAPK9 P45984 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL13967297 0.88 HSD17B10 (0.52) MEN1KMT2ARAB9APTGS2ALDH1A1
SCHEMBL28338084 0.87 MEN1 (0.46) MEN1KMT2ARAB9APTGS2ALDH1A1
SCHEMBL29390160 0.87 KMT2A (0.48) MEN1KMT2ARAB9APTGS2ALDH1A1
SCHEMBL549020 0.87 KMT2A (0.48) MEN1KMT2ARAB9APTGS2ALDH1A1
SCHEMBL30229858 0.86 ALDH1A1 (0.57) MEN1KMT2ARAB9AALDH1A1HSD17B10
SCHEMBL1547477 0.85 MEN1 (0.61) MEN1KMT2ARAB9APTGS2ALDH1A1
SCHEMBL9754447 0.85 KMT2A (0.42) MEN1KMT2ARAB9APTGS2ALDH1A1
SCHEMBL30404870 0.85 KDM4E (0.45) MEN1KMT2ARAB9APTGS2ALDH1A1
SCHEMBL309416 0.85 KDM4E (0.45) MEN1KMT2ARAB9APTGS2ALDH1A1
SCHEMBL1984909 0.85 ALDH1A1 (0.56) MEN1KMT2ARAB9APTGS2ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 59 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-1981238-B Display panel including patterned spacer LG CHEMICAL LTD 2011-09-14 CN claimed
CN-1981238-A Display panel includidng patterned spacer LG CHEMICAL LTD (KR) 2007-06-13 CN claimed
WO-2020217229-A1 POLYCYCLIC COMPOUND AND AN ORGANIC ELECTROLUMINESCENCE DEVICE COMPRISING THE POLYCYCLIC COMPOUND OR THE COMPOSITION IDEMITSU KOSAN CO., LTD. (JP) 2020-10-29 WO disclosed
CN-106133066-B New compound and coloring photosensitive combination 株式会社艾迪科 2019-07-05 CN disclosed
CN-107922589-A Resin composition and cured product 株式会社ADEKA 2018-04-17 CN disclosed
CN-104854155-B Photocurable composition 株式会社ADEKA 2017-08-15 CN disclosed
CN-104507978-B COLORED PHOTOSENSITIVE COMPOSITION 株式会社艾迪科 2017-03-22 CN disclosed
CN-106133066-A New compound and coloring photosensitive combination 株式会社艾迪科 2016-11-16 CN disclosed
CN-102858884-B Dye well coloring photosensitive combination ADEKA CORP. (JP) 2015-10-21 CN disclosed
CN-104854155-A PHOTOCURABLE COMPOSITION ADEKA CORP 2015-08-19 CN disclosed
EP-2673267-B1 1,3-DIOXAN-5-ONE COMPOUNDS MERCK PATENT GMBH (DE) 2015-06-03 EP disclosed
CN-101133363-A Colored alkali-developable photosensitive resin composition and color filters made by using the same TOPPAN PRINTING CO LTD (JP) 2008-02-27 CN disclosed
US-20070197621-A1 Method for the treatment of CNS disorders with substituted 2-imidazoles or imidazole derivatives F. HOFFMANN-LA ROCHE AG, A SWISS COMPANY (CH) 2007-08-23 US disclosed
WO-2007085557-A2 USE OF SUBSTITUTED 2-IMIDAZOLE OF IMIDAZOLINE DERIVATIVES F. HOFFMANN-LA ROCHE AG (CH) 2007-08-02 WO disclosed
CN-1989156-A Fluorine-containing copolymer, alkali-developable resin composition, and alkali-developable photosensitive resin composition ADEKA CORP (JP) 2007-06-27 CN disclosed
CN-1981238-A Display panel includidng patterned spacer LG CHEMICAL LTD (KR) 2007-06-13 CN disclosed
CN-1885163-A Negative resist composition ADMS TECHNOLOGY CO LTD (KR) 2006-12-27 CN disclosed
CN-1842743-A Photosensitive resin composition and LCD using the same LG CHEMICAL LTD (KR) 2006-10-04 CN disclosed
CN-1781057-A Negative resist composition for organic insulating layer of high aperture LCD ADMS TECHNOLOGY CO LTD (KR) 2006-05-31 CN disclosed
CN-1764872-A Transparent, highly heat-resistant polyimide precursor and photosensitive polyimide composition thereof LG CHEMICAL LTD (KR) 2006-04-26 CN disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20070197621-A1 Method for the treatment of CNS disorders with substituted 2-imidazoles or imidazole derivatives GPR119, PER2, MTNR1B MEN1 569/4885KMT2A 805/4885RAB9A 1184/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.