Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CYP1A2 | P05177 | 1/20 | 0.65 |
| ▸ | HTR1A | P08908 | 1/20 | 0.65 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.65 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.65 |
| ▸ | PDE4A | P27815 | 1/20 | 0.65 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.65 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.65 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.65 |
| ▸ | LMNA | P02545 | 1/20 | 0.65 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.65 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.64 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.64 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.49 |
| ▸ | MEN1 | O00255 | 1/20 | 0.47 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6536451 | 0.93 | CYP1A2 (0.64) | CYP1A2HTR1ACYP2D6ADRB3PDE4A | |
| SCHEMBL3997278 | 0.93 | CYP1A2 (0.64) | CYP1A2HTR1ACYP2D6ADRB3PDE4A | |
| SCHEMBL29607926 | 0.93 | CYP1A2 (0.64) | CYP1A2HTR1ACYP2D6ADRB3PDE4A | |
| SCHEMBL23092238 | 0.93 | CYP1A2 (0.64) | CYP1A2HTR1ACYP2D6ADRB3PDE4A | |
| SCHEMBL6536286 | 0.91 | LMNA (0.64) | CYP1A2HTR1ACYP2D6ADRB3PDE4A | |
| SCHEMBL6223476 | 0.85 | ADORA1 (0.59) | PDE4DPDE3ASMN1; SMN2SLC29A1MEN1 | |
| SCHEMBL3465905 | 0.84 | LMNA (0.51) | CYP1A2HTR1ACYP2D6ADRB3PDE4A | |
| SCHEMBL6474053 | 0.84 | SLC29A1 (0.68) | SLC29A1 | |
| SCHEMBL6474066 | 0.84 | SLC29A1 (0.68) | SLC29A1 | |
| Bucladesine SCHEMBL163105 | 0.79 | PDE4A (1.00) | CYP1A2HTR1ACYP2D6ADRB3PDE4A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1466004-A1 | PROCESS FOR THE SELECTIVE ENZYMATIC HYDROLYSIS OF NUCLEOSIDE POLYESTERS | Innovate Biotechnology S.R.L. (IT) | 2004-10-13 | — | — | EP | claimed |
| WO-2003057894-A1 | PROCESS FOR THE SELECTIVE ENZYMATIC HYDROLYSIS OF NUCLEOSIDE POLYESTERS | INNOVATE BIOTECHNOLOGY S.R.L. (IT) | 2003-07-17 | — | — | WO | claimed |
| EP-1466004-A1 | PROCESS FOR THE SELECTIVE ENZYMATIC HYDROLYSIS OF NUCLEOSIDE POLYESTERS | Innovate Biotechnology S.R.L. (IT) | 2004-10-13 | — | — | EP | disclosed |
| WO-2003057894-A1 | PROCESS FOR THE SELECTIVE ENZYMATIC HYDROLYSIS OF NUCLEOSIDE POLYESTERS | INNOVATE BIOTECHNOLOGY S.R.L. (IT) | 2003-07-17 | — | — | WO | disclosed |