Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.64 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.64 |
| ▸ | HTR1A | P08908 | 1/20 | 0.64 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.64 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.64 |
| ▸ | PDE4A | P27815 | 1/20 | 0.64 |
| ▸ | PTGS2 | P35354 | 1/20 | 0.64 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.64 |
| ▸ | PDE3A | Q14432 | 1/20 | 0.64 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.64 |
| ▸ | RXFP1 | Q9HBX9 | 2/20 | 0.62 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.62 |
| ▸ | PRKAB2 | O43741 | 1/20 | 0.53 |
| ▸ | PRKAG1 | P54619 | 1/20 | 0.53 |
| ▸ | PRKAA2 | P54646 | 1/20 | 0.53 |
| ▸ | PRKAA1 | Q13131 | 1/20 | 0.53 |
| ▸ | PRKAG3 | Q9UGI9 | 1/20 | 0.53 |
| ▸ | PRKAG2 | Q9UGJ0 | 1/20 | 0.53 |
| ▸ | PRKAB1 | Q9Y478 | 1/20 | 0.53 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6536080 | 0.91 | CYP1A2 (0.65) | LMNACYP1A2HTR1ACYP2D6ADRB3 | |
| SCHEMBL3997278 | 0.86 | CYP1A2 (0.64) | LMNACYP1A2HTR1ACYP2D6ADRB3 | |
| SCHEMBL29607926 | 0.86 | CYP1A2 (0.64) | LMNACYP1A2HTR1ACYP2D6ADRB3 | |
| SCHEMBL6536451 | 0.86 | CYP1A2 (0.64) | LMNACYP1A2HTR1ACYP2D6ADRB3 | |
| SCHEMBL23092238 | 0.86 | CYP1A2 (0.64) | LMNACYP1A2HTR1ACYP2D6ADRB3 | |
| SCHEMBL20419329 | 0.83 | PRKAB2 (0.62) | LMNACYP1A2HTR1ACYP2D6ADRB3 | |
| SCHEMBL9204101 | 0.80 | PRKAB2 (0.47) | LMNACYP1A2HTR1ACYP2D6ADRB3 | |
| SCHEMBL29721489 | 0.79 | PRKAB2 (0.70) | LMNASMN1; SMN2PRKAB2PRKAG1PRKAA2 | |
| SCHEMBL27209464 | 0.79 | PRKAB2 (0.70) | LMNASMN1; SMN2PRKAB2PRKAG1PRKAA2 | |
| SCHEMBL6536429 | 0.79 | HSP90B1 (0.57) | PDE4DPDE3ASMN1; SMN2PRKAB2PRKAG1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1466004-A1 | PROCESS FOR THE SELECTIVE ENZYMATIC HYDROLYSIS OF NUCLEOSIDE POLYESTERS | Innovate Biotechnology S.R.L. (IT) | 2004-10-13 | — | — | EP | disclosed |
| WO-2003057894-A1 | PROCESS FOR THE SELECTIVE ENZYMATIC HYDROLYSIS OF NUCLEOSIDE POLYESTERS | INNOVATE BIOTECHNOLOGY S.R.L. (IT) | 2003-07-17 | — | — | WO | disclosed |