Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 2/20 | 0.57 |
| ▸ | LTA4H | P09960 | 7/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6535662 | 1.00 | ALOX5AP (0.57) | ALOX5APLTA4HALDH1A1GPR119 | |
| SCHEMBL2200111 | 1.00 | ALOX5AP (0.57) | ALOX5APLTA4HALDH1A1GPR119 | |
| SCHEMBL4324159 | 0.98 | LTA4H (0.58) | ALOX5APLTA4HALDH1A1GPR119 | |
| SCHEMBL4319104 | 0.98 | LTA4H (0.58) | ALOX5APLTA4HALDH1A1GPR119 | |
| SCHEMBL990496 | 0.98 | LTA4H (0.58) | ALOX5APLTA4HALDH1A1GPR119 | |
| SCHEMBL4325249 | 0.94 | ALOX5AP (0.57) | ALOX5APLTA4HALDH1A1GPR119 | |
| SCHEMBL4324215 | 0.94 | ALOX5AP (0.57) | ALOX5APLTA4HALDH1A1GPR119 | |
| SCHEMBL4324207 | 0.94 | ALOX5AP (0.57) | ALOX5APLTA4HALDH1A1GPR119 | |
| SCHEMBL4313051 | 0.94 | ALOX5AP (0.57) | ALOX5APLTA4HALDH1A1 | |
| SCHEMBL4313056 | 0.94 | ALOX5AP (0.57) | ALOX5APLTA4HALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1242081-A4 | CASPASES AND APOPTOSIS | SMITHKLINE BEECHAM CORP (US) | 2004-07-21 | — | — | EP | disclosed |
| EP-1001933-A4 | CASPASES AND APOPTOSIS | SMITHKLINE BEECHAM CORP (US) | 2002-11-06 | — | — | EP | disclosed |
| EP-1242081-A1 | CASPASES AND APOPTOSIS | SmithKline Beecham Corporation (US) | 2002-09-25 | — | — | EP | disclosed |
| WO-2001022966-A1 | CASPASES AND APOPTOSIS | SMITHKLINE BEECHAM CORPORATION (US) | 2001-04-05 | — | — | WO | disclosed |
| EP-1001933-A1 | CASPASES AND APOPTOSIS | SMITHKLINE BEECHAM CORPORATION (US) | 2000-05-24 | — | — | EP | disclosed |
| WO-1999006367-A1 | CASPASES AND APOPTOSIS | SMITHKLINE BEECHAM CORPORATION (US) | 1999-02-11 | — | — | WO | disclosed |