Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALOX5AP | P20292 | 2/20 | 0.57 |
| ▸ | LTA4H | P09960 | 7/20 | 0.55 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.49 |
| ▸ | GPR119 | Q8TDV5 | 2/20 | 0.48 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6535662 | 1.00 | ALOX5AP (0.57) | ALOX5APLTA4HALDH1A1GPR119 | |
| SCHEMBL6536147 | 1.00 | ALOX5AP (0.57) | ALOX5APLTA4HALDH1A1GPR119 | |
| SCHEMBL4324159 | 0.98 | LTA4H (0.58) | ALOX5APLTA4HALDH1A1GPR119 | |
| SCHEMBL4319104 | 0.98 | LTA4H (0.58) | ALOX5APLTA4HALDH1A1GPR119 | |
| SCHEMBL990496 | 0.98 | LTA4H (0.58) | ALOX5APLTA4HALDH1A1GPR119 | |
| SCHEMBL4325249 | 0.94 | ALOX5AP (0.57) | ALOX5APLTA4HALDH1A1GPR119 | |
| SCHEMBL4324215 | 0.94 | ALOX5AP (0.57) | ALOX5APLTA4HALDH1A1GPR119 | |
| SCHEMBL4324207 | 0.94 | ALOX5AP (0.57) | ALOX5APLTA4HALDH1A1GPR119 | |
| SCHEMBL4313051 | 0.94 | ALOX5AP (0.57) | ALOX5APLTA4HALDH1A1 | |
| SCHEMBL4313056 | 0.94 | ALOX5AP (0.57) | ALOX5APLTA4HALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1912994-B1 | ADENINE DERIVATIVES | MERCK PATENT GMBH (DE) | 2014-03-12 | — | — | EP | disclosed |
| US-7977343-B2 | Adenine derivatives | MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) | 2011-07-12 | — | — | US | disclosed |
| US-20100160352-A1 | ADENINE DERIVATIVES | MERCK PATENT GMBH (DE) | 2010-06-24 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100160352-A1 | ADENINE DERIVATIVES | HSP90AA1, TRAP1, HSP90AB1 | ALOX5AP 3894/4885LTA4H 4115/4885ALDH1A1 717/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.