Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.55 |
| ▸ | CYP2C9 | P11712 | 2/20 | 0.55 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.55 |
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.55 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.55 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.55 |
| ▸ | PKM | P14618 | 1/20 | 0.53 |
| ▸ | MEN1 | O00255 | 6/20 | 0.51 |
| ▸ | KMT2A | Q03164 | 6/20 | 0.51 |
| ▸ | MAPT | P10636 | 11/20 | 0.49 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.49 |
| ▸ | LMNA | P02545 | 4/20 | 0.49 |
| ▸ | GAA | P10253 | 1/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.47 |
| ▸ | KCNA5 | P22460 | 1/20 | 0.47 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.47 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6381192 | 0.89 | MAPT (0.52) | SMN1; SMN2CYP1A2CYP2C19PKMMEN1 | |
| SCHEMBL6380429 | 0.86 | MAPT (0.51) | SMN1; SMN2MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL6535395 | 0.78 | GSK3B (0.54) | SMN1; SMN2CYP1A2CYP3A4CYP2D6MEN1 | |
| SCHEMBL6521251 | 0.78 | MAPT (0.57) | SMN1; SMN2CYP1A2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL6536271 | 0.77 | NR1H4 (0.55) | SMN1; SMN2CYP1A2CYP2C9CYP2C19NR1H4 | |
| SCHEMBL11330304 | 0.75 | NR1H4 (0.67) | SMN1; SMN2CYP1A2CYP2C9CYP2C19NR1H4 | |
| SCHEMBL6809806 | 0.75 | MAPT (0.71) | SMN1; SMN2CYP1A2CYP2C9CYP2C19CYP3A4 | |
| SCHEMBL21585123 | 0.75 | KCNA5 (0.55) | SMN1; SMN2CYP1A2CYP3A4CYP2D6MEN1 | |
| SCHEMBL6516526 | 0.74 | GPR84 (0.61) | SMN1; SMN2MEN1KMT2AMAPTALDH1A1 | |
| SCHEMBL6714267 | 0.74 | SSTR2 (0.54) | SMN1; SMN2CYP1A2CYP2C9CYP2C19CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1465858-A2 | PHENY(ALKYL)CARBOXYLIC ACID DERIVATIVES AND DIONIC PHENYLALKYLHETEROCYCLIC DERIVATIVES AND THEIR USE AS MEDICINES WITH SERUM GLUCOSE AND/OR SERUM LIPID LOWERING ACTIVITY | Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. (IT) | 2004-10-13 | — | — | EP | disclosed |
| WO-2003059864-A2 | PHENY(ALKYL)CARBOXYLIC ACID DERIVATIVES AND DIONIC PHENYLALKYLHETEROCYCLIC DERIVATIVES AND THEIR USE AS MEDICINES WITH SERUM GLUCOSE AND/OR SERUM LIPID LOWERING ACTIVITY | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2003-07-24 | — | — | WO | disclosed |