Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NR1H4 | Q96RI1 | 1/20 | 0.55 |
| ▸ | KMT2A | Q03164 | 9/20 | 0.51 |
| ▸ | MEN1 | O00255 | 8/20 | 0.51 |
| ▸ | MAPT | P10636 | 8/20 | 0.48 |
| ▸ | LMNA | P02545 | 4/20 | 0.48 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.48 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.48 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.48 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.48 |
| ▸ | S1PR4 | O95977 | 1/20 | 0.45 |
| ▸ | S1PR1 | P21453 | 1/20 | 0.45 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.45 |
| ▸ | KDM4E | B2RXH2 | 5/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.44 |
| ▸ | HSP90AA1 | P07900 | 3/20 | 0.44 |
| ▸ | HPGD | P15428 | 1/20 | 0.44 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.42 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.42 |
| ▸ | PDGFRB | P09619 | 3/20 | 0.42 |
| ▸ | PDGFRA | P16234 | 3/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6536071 | 0.89 | MTNR1A (0.46) | NR1H4MTNR1AMTNR1BPDGFRBPDGFRA | |
| SCHEMBL6523260 | 0.86 | MTNR1A (0.43) | MAPK1MTNR1AMTNR1BPDGFRBPDGFRA | |
| SCHEMBL6521247 | 0.79 | PPARG (0.53) | KMT2AMEN1MAPK1ALDH1A1MTNR1A | |
| SCHEMBL6535392 | 0.78 | RAB9A (0.48) | MAPTLMNAKDM4EALDH1A1HPGD | |
| SCHEMBL6536272 | 0.77 | SMN1; SMN2 (0.55) | NR1H4KMT2AMEN1MAPTLMNA | |
| SCHEMBL11330304 | 0.75 | NR1H4 (0.67) | NR1H4KMT2AMEN1MAPTLMNA | |
| SCHEMBL7490651 | 0.75 | PKM (0.55) | MAPTMAPK1KDM4EHPGDMTNR1A | |
| SCHEMBL6516521 | 0.74 | MAPT (0.57) | MAPTLMNAMAPK1KDM4EALDH1A1 | |
| SCHEMBL11100803 | 0.74 | NR1H4 (0.72) | NR1H4KMT2AMEN1MAPTLMNA | |
| SCHEMBL9062140 | 0.74 | NR1H4 (0.61) | NR1H4KMT2AMEN1MAPTLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1465858-A2 | PHENY(ALKYL)CARBOXYLIC ACID DERIVATIVES AND DIONIC PHENYLALKYLHETEROCYCLIC DERIVATIVES AND THEIR USE AS MEDICINES WITH SERUM GLUCOSE AND/OR SERUM LIPID LOWERING ACTIVITY | Sigma-Tau Industrie Farmaceutiche Riunite S.p.A. (IT) | 2004-10-13 | — | — | EP | disclosed |
| WO-2003059864-A2 | PHENY(ALKYL)CARBOXYLIC ACID DERIVATIVES AND DIONIC PHENYLALKYLHETEROCYCLIC DERIVATIVES AND THEIR USE AS MEDICINES WITH SERUM GLUCOSE AND/OR SERUM LIPID LOWERING ACTIVITY | SIGMA-TAU INDUSTRIE FARMACEUTICHE RIUNITE S.P.A. (IT) | 2003-07-24 | — | — | WO | disclosed |