Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 8/20 | 0.58 |
| ▸ | ALDH1A1 | P00352 | 6/20 | 0.58 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.58 |
| ▸ | HTR2C | P28335 | 2/20 | 0.55 |
| ▸ | HTR2B | P41595 | 2/20 | 0.55 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.55 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.55 |
| ▸ | MAOA | P21397 | 1/20 | 0.55 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.55 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.55 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.53 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.51 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | MEN1 | O00255 | 2/20 | 0.49 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.49 |
| ▸ | PKM | P14618 | 1/20 | 0.49 |
| ▸ | RAB9A | P51151 | 4/20 | 0.47 |
| ▸ | NPC1 | O15118 | 3/20 | 0.47 |
| ▸ | LMNA | P02545 | 3/20 | 0.46 |
| ▸ | DRD2 | P14416 | 1/20 | 0.46 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12821529 | 0.94 | MAPT (0.58) | MAPTALDH1A1SMN1; SMN2HTR2CHTR2B | |
| SCHEMBL6536539 | 0.92 | MAPT (0.53) | MAPTALDH1A1SMN1; SMN2KDM4EMEN1 | |
| SCHEMBL25524775 | 0.89 | ALDH1A1 (0.69) | MAPTALDH1A1SMN1; SMN2HTR2CHTR2B | |
| SCHEMBL17070937 | 0.85 | METAP1 (0.53) | MAPTALDH1A1SMN1; SMN2CYP1A2KDM4E | |
| SCHEMBL6536469 | 0.83 | METAP1 (0.45) | MAPTALDH1A1SMN1; SMN2SRD5A2KDM4E | |
| SCHEMBL6536297 | 0.83 | MAPT (0.72) | MAPTALDH1A1SMN1; SMN2SLC6A2SRD5A2 | |
| SCHEMBL10922236 | 0.80 | SRD5A2 (0.49) | MAPTALDH1A1SMN1; SMN2HTR2CHTR2B | |
| SCHEMBL15395721 | 0.80 | MAPT (0.50) | MAPTALDH1A1SMN1; SMN2HTR2CHTR2B | |
| SCHEMBL5024789 | 0.79 | KDM4E (0.69) | MAPTALDH1A1SMN1; SMN2HTR2CHTR2B | |
| SCHEMBL19084240 | 0.79 | BACE1 (0.56) | MAPTALDH1A1SMN1; SMN2KDM4EMEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6824709-B2 | A LIQUID CRYSTAL COMPOUND OR LIQUID CRYSTAL POLYMERS, CONTAINING ACRYLATE OR METHACRYLATE FLUORENE GROUP; LIQUID CRYSTAL DISPLAY DEVICE | CHISSO CORPORATION (JP) | 2004-11-30 | — | — | US | disclosed |
| US-20030203128-A1 | Fluorene derivatives and their polymers | JNC PETROCHEMICAL CORPORATION (JP) | 2003-10-30 | — | — | US | disclosed |
| US-4545921-A | Liquid crystals having a type A smectic phase | THOMSON-CSF (FR) | 1985-10-08 | — | — | US | disclosed |