Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | METAP1 | P53582 | 1/20 | 0.45 |
| ▸ | MAPT | P10636 | 4/20 | 0.45 |
| ▸ | NPC1 | O15118 | 1/20 | 0.45 |
| ▸ | RAB9A | P51151 | 1/20 | 0.45 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.44 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.44 |
| ▸ | SRD5A1 | P18405 | 1/20 | 0.43 |
| ▸ | SRD5A2 | P31213 | 1/20 | 0.43 |
| ▸ | CA2 | P00918 | 1/20 | 0.43 |
| ▸ | CA5A | P35218 | 1/20 | 0.43 |
| ▸ | NCEH1 | Q6PIU2 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.41 |
| ▸ | PKM | P14618 | 1/20 | 0.41 |
| ▸ | LMNA | P02545 | 4/20 | 0.41 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.41 |
| ▸ | CYP3A4 | P08684 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 2/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.41 |
| ▸ | TDP2 | O95551 | 1/20 | 0.41 |
| ▸ | TTR | P02766 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6536539 | 0.90 | MAPT (0.53) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL17070937 | 0.84 | METAP1 (0.53) | METAP1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6536307 | 0.83 | MAPT (0.58) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL6536297 | 0.81 | MAPT (0.72) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| SCHEMBL10443829 | 0.79 | SRD5A1 (0.59) | METAP1MAPTNPC1RAB9ASMN1; SMN2 | |
| SCHEMBL4989115 | 0.77 | NCEH1 (0.41) | MAPTSMN1; SMN2ALDH1A1NCEH1POLB | |
| SCHEMBL4610370 | 0.76 | NCEH1 (0.67) | MAPTNPC1RAB9ASMN1; SMN2CA2 | |
| SCHEMBL29624638 | 0.76 | NCEH1 (0.67) | MAPTNPC1RAB9ASMN1; SMN2CA2 | |
| SCHEMBL12821529 | 0.76 | MAPT (0.58) | MAPTNPC1RAB9ASMN1; SMN2ALDH1A1 | |
| Sulfuric Acid SCHEMBL19149045 | 0.76 | METAP1 (0.56) | METAP1MAPTNPC1RAB9ASRD5A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6824709-B2 | A LIQUID CRYSTAL COMPOUND OR LIQUID CRYSTAL POLYMERS, CONTAINING ACRYLATE OR METHACRYLATE FLUORENE GROUP; LIQUID CRYSTAL DISPLAY DEVICE | CHISSO CORPORATION (JP) | 2004-11-30 | — | — | US | disclosed |
| US-20030203128-A1 | Fluorene derivatives and their polymers | JNC PETROCHEMICAL CORPORATION (JP) | 2003-10-30 | — | — | US | disclosed |
| US-4545921-A | Liquid crystals having a type A smectic phase | THOMSON-CSF (FR) | 1985-10-08 | — | — | US | disclosed |