Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.51 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.51 |
| ▸ | TSHR | P16473 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 1/20 | 0.49 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.49 |
| ▸ | HBB | P68871 | 1/20 | 0.49 |
| ▸ | TK2 | O00142 | 3/20 | 0.47 |
| ▸ | P2RY6 | Q15077 | 2/20 | 0.46 |
| ▸ | P2RY14 | Q15391 | 2/20 | 0.46 |
| ▸ | NT5E | P21589 | 1/20 | 0.46 |
| ▸ | THRB | P10828 | 1/20 | 0.44 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.44 |
| ▸ | PYGM | P11217 | 3/20 | 0.44 |
| ▸ | TYMP | P19971 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10895353 | 0.91 | LMNA (0.56) | LMNASMN1; SMN2TSHRMAPTPMP22 | |
| SCHEMBL7806784 | 0.90 | TK2 (0.54) | LMNASMN1; SMN2TSHRMAPTPMP22 | |
| SCHEMBL18503446 | 0.89 | LMNA (0.47) | LMNASMN1; SMN2TSHRMAPTPMP22 | |
| SCHEMBL2583193 | 0.89 | LMNA (0.58) | LMNASMN1; SMN2TSHRMAPTPMP22 | |
| SCHEMBL1055675 | 0.89 | LMNA (0.58) | LMNASMN1; SMN2TSHRMAPTPMP22 | |
| SCHEMBL17198346 | 0.87 | P2RY6 (0.46) | LMNASMN1; SMN2TSHRMAPTPMP22 | |
| SCHEMBL11134817 | 0.85 | LMNA (0.62) | LMNASMN1; SMN2TSHRMAPTPMP22 | |
| SCHEMBL9556674 | 0.82 | TK2 (0.57) | LMNATK2TYMP | |
| SCHEMBL7800239 | 0.82 | P2RY6 (0.54) | LMNASMN1; SMN2TSHRMAPTPMP22 | |
| SCHEMBL2584823 | 0.81 | LMNA (0.49) | LMNASMN1; SMN2TSHRMAPTPMP22 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1466004-A1 | PROCESS FOR THE SELECTIVE ENZYMATIC HYDROLYSIS OF NUCLEOSIDE POLYESTERS | Innovate Biotechnology S.R.L. (IT) | 2004-10-13 | — | — | EP | disclosed |
| WO-2003057894-A1 | PROCESS FOR THE SELECTIVE ENZYMATIC HYDROLYSIS OF NUCLEOSIDE POLYESTERS | INNOVATE BIOTECHNOLOGY S.R.L. (IT) | 2003-07-17 | — | — | WO | disclosed |