Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | P2RY6 | Q15077 | 4/20 | 0.54 |
| ▸ | P2RY14 | Q15391 | 4/20 | 0.54 |
| ▸ | NT5E | P21589 | 1/20 | 0.54 |
| ▸ | LMNA | P02545 | 3/20 | 0.50 |
| ▸ | SMN1; SMN2 | Q16637 | 3/20 | 0.50 |
| ▸ | TSHR | P16473 | 1/20 | 0.50 |
| ▸ | MAPT | P10636 | 1/20 | 0.50 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.50 |
| ▸ | HBB | P68871 | 1/20 | 0.50 |
| ▸ | THRB | P10828 | 1/20 | 0.48 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.48 |
| ▸ | TK2 | O00142 | 2/20 | 0.44 |
| ▸ | DNPH1 | O43598 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6536566 | 0.91 | LMNA (0.54) | P2RY6P2RY14NT5ELMNASMN1; SMN2 | |
| SCHEMBL570475 | 0.91 | LMNA (0.54) | P2RY6P2RY14NT5ELMNASMN1; SMN2 | |
| SCHEMBL2583193 | 0.91 | LMNA (0.58) | P2RY6P2RY14NT5ELMNASMN1; SMN2 | |
| SCHEMBL1055675 | 0.91 | LMNA (0.58) | P2RY6P2RY14NT5ELMNASMN1; SMN2 | |
| SCHEMBL7806784 | 0.90 | TK2 (0.54) | P2RY6P2RY14NT5ELMNASMN1; SMN2 | |
| SCHEMBL10894860 | 0.86 | LMNA (0.50) | P2RY6P2RY14NT5ELMNASMN1; SMN2 | |
| SCHEMBL10894855 | 0.86 | LMNA (0.50) | P2RY6P2RY14NT5ELMNASMN1; SMN2 | |
| SCHEMBL10887395 | 0.86 | LMNA (0.50) | P2RY6P2RY14NT5ELMNASMN1; SMN2 | |
| SCHEMBL10887401 | 0.86 | LMNA (0.50) | P2RY6P2RY14NT5ELMNASMN1; SMN2 | |
| SCHEMBL17198346 | 0.85 | P2RY6 (0.46) | P2RY6P2RY14NT5ELMNASMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0851866-B1 | THERAPEUTIC COMPOUNDS | OXFORD GLYCOSCIENCES UK LTD (GB) | 2001-08-29 | — | — | EP | claimed |
| US-5945406-A | ANTICANCER AGENTS; TREATMENT FOR METASTATIC LIVER CANCER, FUNGAL INFECTIONS, PSORIASIS; USED IN MANUFACTURE OF DRUGSTO PREVENT CELL DIVISION | OXFORD GLYCOSCIENCES (UK) LTD. (GB) | 1999-08-31 | — | — | US | claimed |
| EP-0851866-B1 | THERAPEUTIC COMPOUNDS | OXFORD GLYCOSCIENCES UK LTD (GB) | 2001-08-29 | — | — | EP | disclosed |
| US-5945406-A | ANTICANCER AGENTS; TREATMENT FOR METASTATIC LIVER CANCER, FUNGAL INFECTIONS, PSORIASIS; USED IN MANUFACTURE OF DRUGSTO PREVENT CELL DIVISION | OXFORD GLYCOSCIENCES (UK) LTD. (GB) | 1999-08-31 | — | — | US | disclosed |
| EP-0851866-A1 | THERAPEUTIC COMPOUNDS | Oxford GlycoSciences (UK) Limited (GB) | 1998-07-08 | — | — | EP | disclosed |
| WO-1997000882-A1 | THERAPEUTIC COMPOUNDS | OXFORD GLYCOSCIENCES (UK) LIMITED (GB) | 1997-01-09 | — | — | WO | disclosed |