SCHEMBL6536800

SCHEMBL6536800

c1ccc(Nc2ccc(Nc3ccccc3)c3cc4ccccc4cc23)cc1

nearest known ligand 0.63

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 9/20 0.63
HPGD P15428 6/20 0.63
HSD17B10 Q99714 4/20 0.63
CYP3A4 P08684 3/20 0.63
ALOX15 P16050 3/20 0.63
ATM Q13315 2/20 0.63
TSHR P16473 2/20 0.63
CDC25B P30305 2/20 0.63
TP53 P04637 1/20 0.63
MAPT P10636 8/20 0.58
GAA P10253 7/20 0.58
KMT2A Q03164 7/20 0.58
MEN1 O00255 6/20 0.58
TDP1 Q9NUW8 5/20 0.58
KDM4E B2RXH2 5/20 0.58
RECQL P46063 3/20 0.58
GLA P06280 2/20 0.58
GFER P55789 1/20 0.53
NGLY1 Q96IV0 1/20 0.53
SMN1; SMN2 Q16637 3/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27561763 0.89 CDC25B (0.52) ALDH1A1HPGDHSD17B10CYP3A4ALOX15
SCHEMBL2848293 0.85 ALDH1A1 (0.68) ALDH1A1HPGDHSD17B10CYP3A4ALOX15
SCHEMBL3403976 0.84 ALDH1A1 (0.73) ALDH1A1HPGDHSD17B10CYP3A4ALOX15
SCHEMBL27625922 0.84 ALDH1A1 (0.66) ALDH1A1HPGDHSD17B10CYP3A4ALOX15
SCHEMBL3766360 0.83 MAPT (0.64) ALDH1A1HPGDHSD17B10CYP3A4ALOX15
SCHEMBL11962221 0.80 GAA (0.85) ALDH1A1HPGDHSD17B10CYP3A4ALOX15
SCHEMBL28069110 0.78 ALDH1A1 (0.46) ALDH1A1HPGDHSD17B10CYP3A4ALOX15
Anthracene SCHEMBL27694615 0.78 ALDH1A1 (0.73) ALDH1A1HPGDHSD17B10CYP3A4ALOX15
SCHEMBL29350230 0.77 ALDH1A1 (1.00) ALDH1A1HPGDHSD17B10CYP3A4ALOX15
SCHEMBL19796 0.77 ALDH1A1 (1.00) ALDH1A1HPGDHSD17B10CYP3A4ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6727057-B2 One light-sensitive layer containing an organic silver salt, light sensitive silver halide and a reducing agent and at least one light-insensitive layer on a support, wherein the heat- developable photosensitive material comprises a FUJI PHOTO FILM CO., LTD. (JP) 2004-04-27 US disclosed
US-20030198907-A1 Heat-developable photosensitive material FUJI PHOTO FILM CO., LTD. 2003-10-23 US disclosed
EP-1348997-A1 Heat-developable photosensitive material FUJI PHOTO FILM CO., LTD. (JP) 2003-10-01 EP disclosed