⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8883210 | 0.82 | TSHR (0.30) | — | |
| SCHEMBL6039265 | 0.74 | — | — | |
| SCHEMBL2564193 | 0.72 | TSHR (0.33) | — | |
| SCHEMBL8191872 | 0.70 | TSHR (0.32) | — | |
| SCHEMBL7122438 | 0.70 | TSHR (0.32) | — | |
| SCHEMBL7906828 | 0.68 | — | — | |
| SCHEMBL7873516 | 0.67 | — | — | |
| SCHEMBL7933122 | 0.67 | — | — | |
| SCHEMBL8603642 | 0.65 | — | — | |
| SCHEMBL7553214 | 0.65 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040096397-A1 | Sulfonated diarylrhodamine dyes | APPLERA CORPORATION (US) | 2004-05-20 | — | — | US | disclosed |
| US-5591584-A | CONTAINING A PHOSPHORUS AMIDE GROUP | CHIRON CORPORATION (US) | 1997-01-07 | — | — | US | disclosed |
| US-5580731-A | N-4 modified pyrimidine deoxynucleotides and oligonucleotide probes synthesized therewith | CHIRON CORPORATION (US) | 1996-12-03 | — | — | US | disclosed |
| WO-1996006105-A1 | NOVEL N-4 MODIFIED PYRIMIDINE DEOXYNUCLEOTIDES AND OLIGONUCLEOTIDE PROBES SYNTHESIZED THEREWITH | CHIRON CORPORATION (US) | 1996-02-29 | — | — | WO | disclosed |
| EP-0260032-B1 | Compounds for the cleavage at a specific position of RNA, oligomers employed for the formation of said compounds, and starting materials for the synthesis of said oligomers | AJINOMOTO KK (JP) | 1994-01-26 | — | — | EP | disclosed |
| US-5132204-A | Deprotecting and decomposition to generate light; immunoassay | CHIRON CORPORATION (US) | 1992-07-21 | — | — | US | disclosed |
| WO-1990015040-A1 | CHEMILUMINESCENT DOUBLE-TRIGGERED 1,2-DIOXETANES | CHIRON CORPORATION (US) | 1990-12-13 | — | — | WO | disclosed |
| EP-0401001-A2 | Chemiluminescent doubletriggered 1,2-dioxetanes | CHIRON CORPORATION (US) | 1990-12-05 | — | — | EP | disclosed |
| EP-0260032-A2 | Compounds for the cleavage at a specific position of RNA, oligomers employed for the formation of said compounds, and starting materials for the synthesis of said oligomers | AJINOMOTO CO., INC. (JP) | 1988-03-16 | — | — | EP | disclosed |