⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6854959 | 0.85 | — | — | |
| SCHEMBL2221404 | 0.83 | — | — | |
| SCHEMBL701683 | 0.74 | — | — | |
| SCHEMBL7744369 | 0.72 | — | — | |
| SCHEMBL8637513 | 0.71 | — | — | |
| SCHEMBL497690 | 0.71 | — | — | |
| SCHEMBL6039265 | 0.70 | — | — | |
| SCHEMBL7906828 | 0.69 | — | — | |
| SCHEMBL7122438 | 0.68 | TSHR (0.32) | — | |
| SCHEMBL6536803 | 0.67 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6312953-B1 | MODIFIED OLIGONUCLEOTIDE COMPLEMENTARY TO A TARGET SEQUENCE AND HAVING AT LEAST TWO CROSSLINKING AGENTS COVALENTLY ATTATCHED; GENE EXPRESSION INHIBITION; DNA SEQUENCING; GENETIC MAPPING | EPOCH PHARMACEUTICALS, INC. | 2001-11-06 | — | — | US | disclosed |
| US-5652359-A | Oligonucleotides containing n-methyl thiolated bases having antiviral activity | EPOCH PHARMACEUTICALS, INC. (US) | 1997-07-29 | — | — | US | disclosed |
| WO-1994017092-A1 | BIFUNCTIONAL CROSSLINKING OLIGONUCLEOTIDES ADAPTED FOR LINKING TO A DESIRED GENE SEQUENCE OF INVADING ORGANISM OR CELL | MICROPROBE CORPORATION (US) | 1994-08-04 | — | — | WO | disclosed |