⚠ Novel chemotype — no close known analogue (best Tanimoto < 0.3). Unexplored chemical space relative to ChEMBL.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7906828 | 0.84 | — | — | |
| SCHEMBL8637513 | 0.74 | — | — | |
| SCHEMBL497690 | 0.74 | — | — | |
| SCHEMBL6536803 | 0.74 | — | — | |
| SCHEMBL7873516 | 0.70 | — | — | |
| SCHEMBL6854959 | 0.69 | — | — | |
| SCHEMBL10495860 | 0.69 | — | — | |
| SCHEMBL701683 | 0.69 | — | — | |
| SCHEMBL8883210 | 0.69 | TSHR (0.30) | — | |
| SCHEMBL2221404 | 0.68 | — | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 18 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20240140983-A1 | SINGLE STRANDED DNA ENZYME INHIBITORS | MASSEY UNIVERSITY (NZ) | 2024-05-02 | — | — | US | disclosed |
| US-20060008813-A1 | Compositions and methods of synthesis and use of novel nucleic acid structures | ERITJA RAMON | 2006-01-12 | — | — | US | disclosed |
| US-6831072-B2 | Such as 8-amino-2'deoxyadenosine by treating 8-azido-2'deoxyadenosine with aqueous solution of methylamine or dimethylamine; for targeting nucleic acids without amplification and less use of enzymes | CYGENE, INC. | 2004-12-14 | — | — | US | disclosed |
| US-20030135040-A1 | Compositions and methods of synthesis and use of novel nucleic acid structures | CYGENE, INC. | 2003-07-17 | — | — | US | disclosed |
| US-5624802-A | OLIGONUCLEIC ACIDS SUCH AS DNA OR RNA WITH SINGLE OR DOUBLE STRANDS HAVING COMB OR FORK STRUCTURES | CHIRON CORPORATION (US) | 1997-04-29 | — | — | US | disclosed |
| US-5614362-A | Nucleic acid hybridization assay for hepatitis B virus DNA | CHIRON CORPORATION (US) | 1997-03-25 | — | — | US | disclosed |
| US-5594118-A | Modified N-4 nucleotides for use in amplified nucleic acid hybridization assays | CHIRON CORPORATION (US) | 1997-01-14 | — | — | US | disclosed |
| US-5571670-A | Nucleic acid probes useful in detecting Chlamydia trachomatis and amplified nucleic acid hybridization assays using same | CHIRON CORPORATION (US) | 1996-11-05 | — | — | US | disclosed |
| EP-0469066-B1 | IMPROVED NUCLEIC ACID HYBRIDIZATION ASSAYS FOR HBV EMPLOYING AMPLIFICATION | CHIRON CORP (US) | 1996-05-29 | — | — | EP | disclosed |
| EP-0317077-B1 | Nucleic acid multimers and amplified nucleic acid hybridization assays using same | CHIRON CORP (US) | 1996-01-31 | — | — | EP | disclosed |
| US-5359100-A | Immunoassay | CHIRON CORPORATION (US) | 1994-10-25 | — | — | US | disclosed |
| US-5359053-A | Nucleic acid probes having nucleoside residue; usable with stringent hybridization conditions | G. D. SEARLE & CO. (US) | 1994-10-25 | — | — | US | disclosed |
| US-5134066-A | Hybridization | MONSANTO COMPANY (US) | 1992-07-28 | — | — | US | disclosed |
| EP-0469066-A4 | IMPROVED AMPLIFIED NUCLEIC ACID HYBRIDIZATION ASSAYS FOR HBV | — | 1992-07-08 | — | — | EP | disclosed |
| US-5124246-A | Improved hybridization assays for hepatitis B virus, Neissera gonorrhoeae, penicillin and tetracycline resistance in N. gonorrhoeae and Chlamydia trachomatis | CHIRON CORPORATION (US) | 1992-06-23 | — | — | US | disclosed |
| EP-0469066-A1 | IMPROVED AMPLIFIED NUCLEIC ACID HYBRIDIZATION ASSAYS FOR HBV. | CHIRON CORP (US) | 1992-02-05 | — | — | EP | disclosed |
| WO-1990013667-A1 | IMPROVED AMPLIFIED NUCLEIC ACID HYBRIDIZATION ASSAYS FOR HBV | CHIRON CORPORATION (US) | 1990-11-15 | — | — | WO | disclosed |
| EP-0317077-A1 | Nucleic acid multimers and amplified nucleic acid hybridization assays using same | CHIRON CORPORATION (US) | 1989-05-14 | — | — | EP | disclosed |