SCHEMBL6536816

SCHEMBL6536816

NC(=O)CCC(=O)N1CC1

nearest known ligand 0.59

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
LMNA P02545 3/20 0.54
ALDH1A1 P00352 2/20 0.54
MEN1 O00255 2/20 0.54
KMT2A Q03164 2/20 0.54
TDP1 Q9NUW8 2/20 0.54
KDM4E B2RXH2 1/20 0.54
USP2 O75604 1/20 0.54
CYP3A4 P08684 1/20 0.54
HPGD P15428 1/20 0.54
HSD17B10 Q99714 1/20 0.54
ATM Q13315 1/20 0.48
L3MBTL1 Q9Y468 3/20 0.43
SMN1; SMN2 Q16637 1/20 0.43
GNAI3 P08754 1/20 0.42
GNAI1 P63096 1/20 0.42
NPC1 O15118 1/20 0.40
GAA P10253 1/20 0.39
MAPT P10636 1/20 0.38
NPSR1 Q6W5P4 1/20 0.38
POLB P06746 1/20 0.37

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3950280 0.90 ATM (0.62) LMNAALDH1A1MEN1KMT2ATDP1
SCHEMBL15808655 0.89 HTT (0.50) LMNAALDH1A1MEN1KMT2ATDP1
SCHEMBL15224235 0.88 ATM (0.60) LMNAALDH1A1MEN1KMT2ATDP1
SCHEMBL3943987 0.88 ATM (0.60) LMNAALDH1A1MEN1KMT2ATDP1
SCHEMBL16389743 0.88 ATM (0.60) LMNAALDH1A1MEN1KMT2ATDP1
SCHEMBL15224233 0.88 ATM (0.60) LMNAALDH1A1MEN1KMT2ATDP1
SCHEMBL2344320 0.87 ATM (0.58) LMNAALDH1A1MEN1KMT2ATDP1
SCHEMBL674446 0.86 LMNA (0.68) LMNAALDH1A1MEN1KMT2ATDP1
SCHEMBL23414183 0.85 GNAI3 (0.58) LMNAALDH1A1MEN1KMT2ATDP1
SCHEMBL22209196 0.85 GNAI3 (0.58) LMNAALDH1A1MEN1KMT2ATDP1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-6677427-B1 REACTING AT LEAST ONE DIESTER AND AT LEAST ONE POLYAMINE IN PRESENCE OF A HYDROLYTIC ENZYME TO PREPARE POLYAMIDE HERCULES INCORPORATED 2004-01-13 US claimed
EP-1290211-A2 ENZYME-CATALYZED POLYAMIDES AND COMPOSITIONS AND PROCESSES OF PREPARING AND USING THE SAME HERCULES INCORPORATED (US) 2003-03-12 EP claimed
WO-2001096588-A2 ENZYME-CATALYZED POLYAMIDES AND COMPOSITIONS AND PROCESSES OF PREPARING AND USING THE SAME HERCULES INCORPORATED (US) 2001-12-20 WO claimed
CN-107229197-B Toner composition for magnetic ink character recognition 施乐公司 2022-07-01 CN disclosed
CN-107179661-B Metal toner composition 施乐公司 2020-04-17 CN disclosed
US-6677427-B1 REACTING AT LEAST ONE DIESTER AND AT LEAST ONE POLYAMINE IN PRESENCE OF A HYDROLYTIC ENZYME TO PREPARE POLYAMIDE HERCULES INCORPORATED 2004-01-13 US disclosed
EP-1290211-A2 ENZYME-CATALYZED POLYAMIDES AND COMPOSITIONS AND PROCESSES OF PREPARING AND USING THE SAME HERCULES INCORPORATED (US) 2003-03-12 EP disclosed
WO-2001096588-A2 ENZYME-CATALYZED POLYAMIDES AND COMPOSITIONS AND PROCESSES OF PREPARING AND USING THE SAME HERCULES INCORPORATED (US) 2001-12-20 WO disclosed
US-5807625-A POLYMERIC PROTECTING COMPOSITION WHICH IS A LIGHT-TRANSPARENT THERMOPLASTIC HAVING A SPECIFIC MELTING POINT RANGE AND IS A BARRIER FOR ANY INK COMPONENT WHICH IS CAPABLE OF IRREVERSIBLY INTERFERING WITH PHOTOCHROMIC REACTION SITES SICPA HOLDING S.A. (CH) 1998-09-15 US disclosed
US-5630869-A THERMOPLASTIC RESINS WITH OXYGEN BARRIERS, MELTING, COOLING TO FORM A SOLID SOLUTION, BREAKING AND ACCUMULATION SICIPA HOLDING S.A. (CH) 1997-05-20 US disclosed
EP-0327788-B1 Reversibly photochromic printing inks SICPA HOLDING SA (CH) 1993-11-24 EP disclosed
EP-0327788-A2 Reversibly photochromic printing inks SICPA HOLDING S.A. (CH) 1989-08-16 EP disclosed