Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KCNMA1 | Q12791 | 1/20 | 0.49 |
| ▸ | MAPT | P10636 | 6/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | MEN1 | O00255 | 2/20 | 0.43 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.43 |
| ▸ | TDP1 | Q9NUW8 | 3/20 | 0.43 |
| ▸ | L3MBTL1 | Q9Y468 | 3/20 | 0.43 |
| ▸ | MAPK1 | P28482 | 2/20 | 0.43 |
| ▸ | ATM | Q13315 | 1/20 | 0.42 |
| ▸ | HCAR3 | P49019 | 5/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | HTT | P42858 | 1/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6536820 | 1.00 | KCNMA1 (0.49) | KCNMA1MAPTLMNAMEN1KMT2A | |
| SCHEMBL6538200 | 0.83 | MAPT (0.57) | KCNMA1MAPTLMNAMEN1KMT2A | |
| SCHEMBL6538196 | 0.83 | MAPT (0.57) | KCNMA1MAPTLMNAMEN1KMT2A | |
| SCHEMBL6537866 | 0.83 | APP (0.54) | KCNMA1MAPTLMNAMEN1KMT2A | |
| SCHEMBL6537524 | 0.83 | ALDH1A1 (0.58) | KCNMA1MAPTLMNAKMT2AMAPK1 | |
| SCHEMBL6537862 | 0.83 | APP (0.54) | KCNMA1MAPTLMNAMEN1KMT2A | |
| SCHEMBL8472886 | 0.83 | ALDH1A1 (0.58) | KCNMA1MAPTLMNAKMT2AMAPK1 | |
| SCHEMBL6980498 | 0.79 | MEN1 (0.53) | KCNMA1MAPTMEN1KMT2ATDP1 | |
| SCHEMBL6980493 | 0.79 | MEN1 (0.53) | KCNMA1MAPTMEN1KMT2ATDP1 | |
| SCHEMBL7532822 | 0.79 | TDP1 (0.50) | KCNMA1MAPTLMNAMEN1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 4 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0876345-B1 | HETEROCYCLIC COMPOUNDS AS H+-ATPASES | FUJISAWA PHARMACEUTICAL CO (JP) | 2004-08-18 | — | — | EP | disclosed |
| US-6008230-A | TREATING BONE DISEASES CAUSED BY ABNORMAL BONE METABOLISM IN HUMAN BEING OR ANIMALS AS THE INHIBITORS OF BONE RESORPTION OR THE INHIBITORS OF BONE METASTASIS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1999-12-28 | — | — | US | disclosed |
| EP-0876345-A1 | HETEROCYCLIC COMPOUNDS AS H+-ATPASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1998-11-11 | — | — | EP | disclosed |
| WO-1997014681-A1 | HETEROCYCLIC COMPOUNDS AS H+-ATPASES | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 1997-04-24 | — | — | WO | disclosed |