Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 4/20 | 0.63 |
| ▸ | LMNA | P02545 | 1/20 | 0.63 |
| ▸ | PKM | P14618 | 1/20 | 0.59 |
| ▸ | RCE1 | Q9Y256 | 1/20 | 0.42 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.41 |
| ▸ | MAPT | P10636 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 1/20 | 0.41 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.41 |
| ▸ | HSP90AA1 | P07900 | 2/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.40 |
| ▸ | USP2 | O75604 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 1/20 | 0.40 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.40 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.39 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11156584 | 0.83 | HTT (0.52) | HTTLMNAPKMALDH1A1MEN1 | |
| SCHEMBL585863 | 0.79 | HTT (0.53) | HTTLMNAPKMRCE1ALDH1A1 | |
| SCHEMBL4630376 | 0.79 | HTT (0.71) | HTTLMNAPKMALDH1A1MEN1 | |
| SCHEMBL10579123 | 0.79 | HTT (0.71) | HTTLMNAPKMALDH1A1MEN1 | |
| SCHEMBL14922180 | 0.78 | HTT (0.47) | HTTLMNAPKMRCE1ALDH1A1 | |
| SCHEMBL6700939 | 0.77 | ALDH1A1 (0.44) | HTTLMNAPKMALDH1A1MEN1 | |
| SCHEMBL622455 | 0.77 | ALDH1A1 (0.44) | HTTLMNAPKMALDH1A1MEN1 | |
| SCHEMBL7531782 | 0.77 | ALDH1A1 (0.44) | HTTLMNAPKMALDH1A1MEN1 | |
| SCHEMBL17870917 | 0.77 | HTT (0.45) | HTTLMNAPKMRCE1ALDH1A1 | |
| Vitamin K3H2 SCHEMBL297164 | 0.77 | HTT (1.00) | HTTLMNAPKMALDH1A1MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 9 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6827836-B2 | With high para selectivity; hydrogen bromide not generated as a by-product; | GENERAL ELECTRIC COMPANY | 2004-12-07 | — | — | US | claimed |
| WO-2004050954-A1 | METHOD OF PREPARING BROMINATED HYDROXY AROMATIC COMPOUNDS | GENERAL ELECTRIC COMPANY (US) | 2004-06-17 | — | — | WO | claimed |
| US-20040104126-A1 | Method of preparing brominated hydroxy aromatic compounds | GENERAL ELECTRIC COMPANY | 2004-06-03 | — | — | US | claimed |
| US-6827836-B2 | With high para selectivity; hydrogen bromide not generated as a by-product; | GENERAL ELECTRIC COMPANY | 2004-12-07 | — | — | US | disclosed |
| WO-2004050954-A1 | METHOD OF PREPARING BROMINATED HYDROXY AROMATIC COMPOUNDS | GENERAL ELECTRIC COMPANY (US) | 2004-06-17 | — | — | WO | disclosed |
| US-20040104126-A1 | Method of preparing brominated hydroxy aromatic compounds | GENERAL ELECTRIC COMPANY | 2004-06-03 | — | — | US | disclosed |
| EP-0026872-B1 | PLANT GROWTH REGULATING PRODUCTS CONTAINING SUBSTITUTED ALKYLAMMONIUM SALTS AND THEIR USE | BASF Aktiengesellschaft (DE) | 1983-03-09 | — | — | EP | disclosed |
| US-4327214-A | Substituted alkylammonium salts, the manufacture thereof, the use thereof for regulating plant growth, and agents therefor | BASF AKTIENGESELLSCHAFT (DE) | 1982-04-27 | — | — | US | disclosed |
| EP-0026872-A1 | Plant growth regulating products containing substituted alkylammonium salts and their use | BASF Aktiengesellschaft (DE) | 1981-04-15 | — | — | EP | disclosed |