Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 3/20 | 0.71 |
| ▸ | LMNA | P02545 | 2/20 | 0.71 |
| ▸ | PKM | P14618 | 1/20 | 0.65 |
| ▸ | CYP1A2 | P05177 | 4/20 | 0.50 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.48 |
| ▸ | MAPT | P10636 | 3/20 | 0.44 |
| ▸ | NPC1 | O15118 | 2/20 | 0.44 |
| ▸ | RAB9A | P51151 | 2/20 | 0.44 |
| ▸ | MEN1 | O00255 | 2/20 | 0.44 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.44 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.44 |
| ▸ | CTDSP1 | Q9GZU7 | 1/20 | 0.44 |
| ▸ | CYP2A6 | P11509 | 2/20 | 0.43 |
| ▸ | PTGS1 | P23219 | 2/20 | 0.43 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.43 |
| ▸ | TTR | P02766 | 1/20 | 0.43 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.42 |
| ▸ | MITF | O75030 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL10579123 | 0.85 | HTT (0.71) | HTTLMNAPKMCYP1A2ALDH1A1 | |
| Vitamin K3H2 SCHEMBL297164 | 0.83 | HTT (1.00) | HTTLMNAPKMCYP1A2ALDH1A1 | |
| SCHEMBL10578988 | 0.83 | LMNA (0.56) | HTTLMNAPKMCYP1A2ALDH1A1 | |
| Vitamin K3H2 SCHEMBL29525544 | 0.83 | HTT (1.00) | HTTLMNAPKMCYP1A2ALDH1A1 | |
| SCHEMBL29771847 | 0.83 | HTT (0.68) | HTTLMNAPKMCYP1A2ALDH1A1 | |
| SCHEMBL11430369 | 0.83 | HTT (0.68) | HTTLMNAPKMCYP1A2ALDH1A1 | |
| Vitamin K3H2 SCHEMBL2887680 | 0.81 | HTT (0.95) | HTTLMNAPKMCYP1A2ALDH1A1 | |
| SCHEMBL21771153 | 0.79 | HTT (0.63) | HTTLMNAPKMCYP1A2ALDH1A1 | |
| SCHEMBL7557418 | 0.79 | HTT (0.63) | HTTLMNAPKMCYP1A2ALDH1A1 | |
| SCHEMBL318448 | 0.79 | PKM (1.00) | HTTLMNAPKMCYP1A2ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 50 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| CN-118791365-A | Naphthol alkylation process | 帝斯曼知识产权资产管理有限公司 | 2024-10-18 | — | — | CN | disclosed |
| EP-4446305-A1 | AN ALKYLATION PROCESS OF NAPHTHOL | DSM IP Assets B.V. (NL) | 2024-10-16 | — | — | EP | disclosed |
| US-11707452-B2 | Modulators of alpha-synuclein proteolysis and associated methods of use | ARVINAS OPERATIONS, INC. (US) | 2023-07-25 | — | — | US | disclosed |
| US-11707452-B2 | Modulators of alpha-synuclein proteolysis and associated methods of use | ARVINAS OPERATIONS, INC. (US) | 2023-07-25 | — | — | US | disclosed |
| US-9434844-B2 | Additive, composition comprising it and use thereof | INEOS EUROPE AG (CH) | 2016-09-06 | — | — | US | disclosed |
| US-20140275391-A1 | ADDITIVE, COMPOSITION COMPRISING IT AND USE THEREOF | BARCLAYS BANK PLC (GB) | 2014-09-18 | — | — | US | disclosed |
| US-8097615-B2 | Neurofibrillary labels | WISTA LABORATORIES LTD. (SG) | 2012-01-17 | — | — | US | disclosed |
| EP-1972351-B1 | Method for inactivation of microorganisms using photosensitizers | CARIDIANBCT BIOTECHNOLOGIES LLC (US) | 2011-05-11 | — | — | EP | disclosed |
| US-20100285605-A1 | Neurofibrillary labels | WISTA LABORATORIES LTD. | 2010-11-11 | — | — | US | disclosed |
| US-7744804-B2 | Laser-transmissible composition and method of laser welding | ORIENT CHEMICAL INDUSTRIES, LTD. (JP) | 2010-06-29 | — | — | US | disclosed |
| EP-1149852-A1 | AROMATIC POLYCARBONATE, PROCESS FOR PRODUCING THE SAME, AND MOLDED ARTICLE | TEIJIN LIMITED (JP) | 2001-10-31 | — | — | EP | disclosed |
| WO-1995023183-A1 | LIQUID CRYSTALLINE POLYMER BLENDS AND PROCESSES FOR THE PREPARATION THEREOF | NESTE OY (FI) | 1995-08-31 | — | — | WO | disclosed |
| EP-0164227-A2 | Neoalkoxy organo-titanates and organo-zirconates useful as coupling and polymer processing agents | KENRICH PETROCHEMICALS, INC. (US) | 1985-12-11 | — | — | EP | disclosed |
| US-4499000-A | Power-transmission method uses spirocyclic ketals | BAYER AKTIENGESELLSCHAFT (DE) | 1985-02-12 | — | — | US | disclosed |
| EP-0047448-B1 | HYDRAULIC FLUID | BAYER AG (DE) | 1983-09-21 | — | — | EP | disclosed |
| EP-0026872-B1 | PLANT GROWTH REGULATING PRODUCTS CONTAINING SUBSTITUTED ALKYLAMMONIUM SALTS AND THEIR USE | BASF Aktiengesellschaft (DE) | 1983-03-09 | — | — | EP | disclosed |
| US-4327214-A | Substituted alkylammonium salts, the manufacture thereof, the use thereof for regulating plant growth, and agents therefor | BASF AKTIENGESELLSCHAFT (DE) | 1982-04-27 | — | — | US | disclosed |
| EP-0047448-A2 | Hydraulic fluid | BAYER AG (DE) | 1982-03-17 | — | — | EP | disclosed |
| EP-0026872-A1 | Plant growth regulating products containing substituted alkylammonium salts and their use | BASF Aktiengesellschaft (DE) | 1981-04-15 | — | — | EP | disclosed |
| US-3960972-A | FROM OLEFINS AND FORMALDEHYDE, PHENOL PROMOTER | PHILLIPS PETROLEUM COMPANY (US) | 1976-06-01 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-11707452-B2 | Modulators of alpha-synuclein proteolysis and associated methods of use | UCHL1, ADRM1, CRBN | HTT 47/4885LMNA 1946/4885PKM 3372/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.