SCHEMBL6537028

SCHEMBL6537028

CCCc1cc(C(C)(C)C)c(O)cc1C

nearest known ligand 0.54

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALOX15 P16050 5/20 0.54
CYP2C9 P11712 5/20 0.54
CYP2C19 P33261 4/20 0.54
TP53 P04637 3/20 0.54
CYP2D6 P10635 2/20 0.54
ALDH1A1 P00352 5/20 0.50
SMN1; SMN2 Q16637 4/20 0.50
HIF1A Q16665 3/20 0.50
CYP3A4 P08684 2/20 0.50
CYP1A2 P05177 2/20 0.50
KDM4E B2RXH2 1/20 0.50
MAPT P10636 1/20 0.50
ATP2A2 P16615 1/20 0.50
ATP2A3 Q93084 1/20 0.50
TSHR P16473 1/20 0.50
MAPK1 P28482 1/20 0.50
TDP1 Q9NUW8 1/20 0.50
HSD17B10 Q99714 2/20 0.40
LMNA P02545 2/20 0.39
HPGD P15428 1/20 0.39

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL27494856 0.93 CYP2C9 (0.50) ALOX15CYP2C9CYP2C19TP53CYP2D6
SCHEMBL9230440 0.90 ALOX15 (0.56) ALOX15CYP2C9CYP2C19TP53CYP2D6
SCHEMBL529614 0.89 ALOX15 (0.51) ALOX15CYP2C9CYP2C19TP53CYP2D6
SCHEMBL3125086 0.88 ALOX15 (0.50) ALOX15CYP2C9CYP2C19TP53CYP2D6
SCHEMBL5073267 0.87 ALOX15 (0.52) ALOX15CYP2C9CYP2C19TP53CYP2D6
SCHEMBL30471645 0.87 ALOX15 (0.52) ALOX15CYP2C9CYP2C19TP53CYP2D6
SCHEMBL2163484 0.87 ALOX15 (0.52) ALOX15CYP2C9CYP2C19TP53CYP2D6
SCHEMBL9765959 0.85 CYP2C9 (0.46) ALOX15CYP2C9CYP2C19TP53CYP2D6
SCHEMBL5083346 0.85 ALOX15 (0.48) ALOX15CYP2C9CYP2C19TP53CYP2D6
SCHEMBL28382405 0.85 ALOX15 (0.48) ALOX15CYP2C9CYP2C19TP53CYP2D6

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 34 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0326223-A2 Copolymer composition SHELL INTERNATIONALE RESEARCHMAATSCHAPPIJ B.V. (NL) 1989-08-02 EP claimed
JP-58057990-A None JP disclosed
CN-118103424-A Modified epoxy resin and electrodeposition paint 关西涂料株式会社 2024-05-28 CN disclosed
CN-117264184-A Method for producing polybutylene terephthalate resin 东丽株式会社 2023-12-22 CN disclosed
CN-101472995-B Polycarbonate compositions and articles formed therefrom SABIC INNOVATIVE PLASTICS IP B.V. (NL) 2011-12-28 CN disclosed
CN-101472994-A Polycarbonate compositions and articles formed therefrom GEN ELECTRIC (NL) 2009-07-01 CN disclosed
CN-101472995-A Polycarbonate compositions and articles formed therefrom GEN ELECTRIC (NL) 2009-07-01 CN disclosed
CN-100504627-C Resin fine particles for toner raw material, aqueous dispersion system thereof, and toner MITSUI CHEMICALS INC (JP) 2009-06-24 CN disclosed
CN-101400763-A Halogen-free polycarbonate compositions and articles formed therefrom SABIC INNOVATIVE PLASTICS IP (NL) 2009-04-01 CN disclosed
CN-101384684-A Polycarbonate compositions and articles formed therefrom GEN ELECTRIC (US) 2009-03-11 CN disclosed
US-20020061818-A1 Heat-sensitive recording material FUJI PHOTO FILM CO., LTD. 2002-05-23 US disclosed
CN-1318776-A Development composition and thermosensitive recording material MITSUI CHEMICALS INC (JP) 2001-10-24 CN disclosed
CN-1276299-A Color developing composition, aqueous dispersion liquid, recording paper and color developing ink MITSUI CHEMICALS INC (JP) 2000-12-13 CN disclosed
EP-0433024-B1 Colour recording medium containing leuco dye FUJI PHOTO FILM CO LTD (JP) 1994-09-21 EP disclosed
EP-0334606-B1 Heat-sensitive recording sheet materials FUJI PHOTO FILM CO LTD (JP) 1994-08-10 EP disclosed
EP-0462770-B1 Thermosensitive recording material FUJI PHOTO FILM CO LTD (JP) 1994-04-20 EP disclosed
EP-0462770-A1 Thermosensitive recording material FUJI PHOTO FILM CO., LTD. (JP) 1991-12-27 EP disclosed
EP-0433024-A1 Colour recording medium containing leuco dye FUJI PHOTO FILM CO., LTD. (JP) 1991-06-19 EP disclosed
EP-0357409-A2 Heat-sensitive recording material FUJI PHOTO FILM CO., LTD. (JP) 1990-03-07 EP disclosed
JP-S5857990-A HEAT-SENSITIVE RECORDING PAPER FUJI PHOTO FILM CO LTD 1983-04-06 JP disclosed